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    NR1H4 nuclear receptor subfamily 1 group H member 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 695618, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NR1H4provided by VGNC
    Official Full Name
    nuclear receptor subfamily 1 group H member 4provided by VGNC
    Primary source
    VGNC:VGNC:75506
    See related
    Ensembl:ENSMMUG00000003571
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See NR1H4 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (100314896..100399668)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (100393402..100478064)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene SCY1 like pseudokinase 2 Neighboring gene small nucleolar RNA U13 Neighboring gene solute carrier family 17 member 8 Neighboring gene phosphatidylinositol N-acetylglucosaminyltransferase subunit A pseudogene Neighboring gene growth arrest specific 2 like 3 Neighboring gene anoctamin 4 Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables bile acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in bile acid signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    bile acid receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      100314896..100399668
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015152561.2 → XP_015008047.1  bile acid receptor isoform X3

      Conserved Domains (2) summary
      cd06936
      Location:268 → 488
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cl02596
      Location:141 → 228
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

    2. XM_015152563.2 → XP_015008049.1  bile acid receptor isoform X6

      UniProtKB/TrEMBL
      F7ETB1
      Related
      ENSMMUP00000004758.4, ENSMMUT00000005050.4
      Conserved Domains (2) summary
      cd06936
      Location:251 → 471
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124 → 211
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

    3. XM_001090297.4 → XP_001090297.1  bile acid receptor isoform X7

      See identical proteins and their annotated locations for XP_001090297.1

      Conserved Domains (2) summary
      cd06936
      Location:247 → 467
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:124 → 207
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

    4. XM_015152559.2 → XP_015008045.1  bile acid receptor isoform X1

      Conserved Domains (2) summary
      cd06936
      Location:278 → 498
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cl02596
      Location:151 → 238
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

    5. XM_015152560.2 → XP_015008046.1  bile acid receptor isoform X2

      Conserved Domains (2) summary
      cd06936
      Location:274 → 494
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:151 → 234
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

    6. XM_015152562.2 → XP_015008048.1  bile acid receptor isoform X4

      UniProtKB/TrEMBL
      F6U1W4
      Related
      ENSMMUP00000038826.3, ENSMMUT00000045780.3
      Conserved Domains (2) summary
      cd06936
      Location:261 → 481
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:134 → 221
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers

    7. XM_001090182.4 → XP_001090182.1  bile acid receptor isoform X5

      See identical proteins and their annotated locations for XP_001090182.1

      UniProtKB/TrEMBL
      F6U1W4
      Conserved Domains (2) summary
      cd06936
      Location:257 → 477
      NR_LBD_Fxr; The ligand binding domain of Farnesoid X receptor:a member of the nuclear receptor superfamily of ligand-activated transcription factors
      cd06962
      Location:134 → 217
      NR_DBD_FXR; DNA-binding domain of Farnesoid X receptor (FXR) family is composed of two C4-type zinc fingers
    Nucleotide Protein
    Heading Accession and Version

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