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    FGFR4 fibroblast growth factor receptor 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 698494, updated on 17-Aug-2024

    Summary

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    Official Symbol
    FGFR4provided by VGNC
    Official Full Name
    fibroblast growth factor receptor 4provided by VGNC
    Primary source
    VGNC:VGNC:72654
    See related
    Ensembl:ENSMMUG00000011033
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See FGFR4 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (174560238..174571316)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (175713976..175724827)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene heat shock factor-binding protein 1 pseudogene Neighboring gene ubiquitin interaction motif containing 1 Neighboring gene zinc finger protein 346 Neighboring gene nuclear receptor binding SET domain protein 1 Neighboring gene protein arginine N-methyltransferase 1 pseudogene Neighboring gene RAB24, member RAS oncogene family

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables fibroblast growth factor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables fibroblast growth factor receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fibroblast growth factor receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of ERK1 and ERK2 cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of bile acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    fibroblast growth factor receptor 4
    XP_014996982.2
    XP_028705775.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      174560238..174571316
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015141496.2 → XP_014996982.2  fibroblast growth factor receptor 4

      UniProtKB/TrEMBL
      F7CEB0, F7CEB6
      Related
      ENSMMUP00000006528.3, ENSMMUT00000006942.4
      Conserved Domains (4) summary
      cd05858
      Location:264 → 351
      Ig3_FGFR-2; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor 2 (FGFR2)
      smart00408
      Location:50 → 107
      IGc2; Immunoglobulin C-2 Type
      cl11960
      Location:157 → 241
      Ig; Immunoglobulin domain
      cl21453
      Location:454 → 767
      PKc_like; Protein Kinases, catalytic domain

    2. XM_028849942.1 → XP_028705775.1  fibroblast growth factor receptor 4

      UniProtKB/TrEMBL
      F7CEB0, F7CEB6
      Conserved Domains (4) summary
      cd05858
      Location:264 → 351
      Ig3_FGFR-2; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor 2 (FGFR2)
      smart00408
      Location:50 → 107
      IGc2; Immunoglobulin C-2 Type
      cl11960
      Location:157 → 241
      Ig; Immunoglobulin domain
      cl21453
      Location:454 → 767
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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