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    ALDH1L2 aldehyde dehydrogenase 1 family member L2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 701242, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ALDH1L2provided by VGNC
    Official Full Name
    aldehyde dehydrogenase 1 family member L2provided by VGNC
    Primary source
    VGNC:VGNC:81356
    See related
    Ensembl:ENSMMUG00000005797
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ALDH1L2 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (104748862..104819328, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (104955777..105017898, complement)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene keratin, type I cytoskeletal 18 pseudogene Neighboring gene NOP protein chaperone 1 Neighboring gene WASH complex subunit 4 Neighboring gene uncharacterized LOC114670939 Neighboring gene adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables aldehyde dehydrogenase (NAD+) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables formyltetrahydrofolate dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in 10-formyltetrahydrofolate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in one-carbon metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitochondrial 10-formyltetrahydrofolate dehydrogenase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      104748862..104819328 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015152659.2 → XP_015008145.2  mitochondrial 10-formyltetrahydrofolate dehydrogenase isoform X1

      UniProtKB/TrEMBL
      G7N5B5
      Conserved Domains (4) summary
      cd07140
      Location:439 → 910
      ALDH_F1L_FTFDH; 10-formyltetrahydrofolate dehydrogenase, ALDH family 1L
      cd08647
      Location:23 → 225
      FMT_core_FDH_N; 10-formyltetrahydrofolate dehydrogenase (FDH), N-terminal hydrolase domain
      cd08703
      Location:228 → 327
      FDH_Hydrolase_C; The C-terminal subdomain of the hydrolase domain on the bi-functional protein 10-formyltetrahydrofolate dehydrogenase
      pfam00550
      Location:346 → 410
      PP-binding; Phosphopantetheine attachment site

    2. XM_001089566.4 → XP_001089566.1  mitochondrial 10-formyltetrahydrofolate dehydrogenase isoform X2

      UniProtKB/TrEMBL
      F6W9P8, G7N5B5
      Related
      ENSMMUP00000038748.1, ENSMMUT00000045704.3
      Conserved Domains (5) summary
      cd07140
      Location:439 → 923
      ALDH_F1L_FTFDH; 10-formyltetrahydrofolate dehydrogenase, ALDH family 1L
      cd08647
      Location:23 → 225
      FMT_core_FDH_N; 10-formyltetrahydrofolate dehydrogenase (FDH), N-terminal hydrolase domain
      cd08703
      Location:228 → 327
      FDH_Hydrolase_C; The C-terminal subdomain of the hydrolase domain on the bi-functional protein 10-formyltetrahydrofolate dehydrogenase
      COG0223
      Location:22 → 326
      Fmt; Methionyl-tRNA formyltransferase [Translation, ribosomal structure and biogenesis]
      pfam00550
      Location:346 → 410
      PP-binding; Phosphopantetheine attachment site

    3. XM_028829819.1 → XP_028685652.1  mitochondrial 10-formyltetrahydrofolate dehydrogenase isoform X3

      UniProtKB/TrEMBL
      G7N5B5
      Conserved Domains (4) summary
      cd07140
      Location:293 → 764
      ALDH_F1L_FTFDH; 10-formyltetrahydrofolate dehydrogenase, ALDH family 1L
      cd08703
      Location:82 → 181
      FDH_Hydrolase_C; The C-terminal subdomain of the hydrolase domain on the bi-functional protein 10-formyltetrahydrofolate dehydrogenase
      pfam00550
      Location:200 → 264
      PP-binding; Phosphopantetheine attachment site
      cl00395
      Location:2 → 79
      FMT_core; Formyltransferase, catalytic core domain
    Nucleotide Protein
    Heading Accession and Version

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