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    FMO3 flavin containing dimethylaniline monoxygenase 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 574244, updated on 17-Aug-2024

    Summary

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    Official Symbol
    FMO3provided by VGNC
    Official Full Name
    flavin containing dimethylaniline monoxygenase 3provided by VGNC
    Primary source
    VGNC:VGNC:99953
    See related
    Ensembl:ENSMMUG00000007952
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See FMO3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (28406164..28431007)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (196516722..196541616, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene maestro heat like repeat family member 9 Neighboring gene alkylated DNA repair protein alkB homolog 8-like Neighboring gene putative dimethylaniline monooxygenase [N-oxide-forming] 6 Neighboring gene peroxisomal membrane protein PMP34 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Population distribution of human flavin-containing monooxygenase form 3: gene polymorphisms. Cashman JR, et al. Drug Metab Dispos, 2001 Dec. PMID 11717182
    2. Molecular and functional characterization of flavin-containing monooxygenases in cynomolgus macaque. Uno Y, et al. Biochem Pharmacol, 2013 Jun 15. PMID 23623750
    3. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables N,N-dimethylaniline monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables NADP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    flavin-containing monooxygenase 3; dimethylaniline monooxygenase [N-oxide-forming] 3
    Names
    FMO 3
    dimethylaniline oxidase 3
    flavin containing monooxygenase 3
    flavin-containing monooxygenase form 3
    hepatic flavin-containing monooxygenase 3
    trimethylamine monooxygenase
    NP_001028065.1
    XP_014978702.1
    XP_014978710.1
    XP_014978717.1
    XP_028706531.1
    XP_028706553.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001032893.1 → NP_001028065.1  flavin-containing monooxygenase 3

      See identical proteins and their annotated locations for NP_001028065.1

      Status: PROVISIONAL

      Source sequence(s)
      AY063498
      UniProtKB/Swiss-Prot
      Q8SPQ7
      UniProtKB/TrEMBL
      A0A023JCQ5
      Conserved Domains (2) summary
      pfam00743
      Location:2 → 532
      FMO-like; Flavin-binding monooxygenase-like
      cl21454
      Location:6 → 220
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      28406164..28431007
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015123216.2 → XP_014978702.1  dimethylaniline monooxygenase [N-oxide-forming] 3 isoform X1

      UniProtKB/TrEMBL
      A0A023JCQ5, F7HQX7
      Related
      ENSMMUP00000010434.3, ENSMMUT00000011127.4
      Conserved Domains (1) summary
      pfam00743
      Location:2 → 532
      FMO-like; Flavin-binding monooxygenase-like

    2. XM_028850698.1 → XP_028706531.1  dimethylaniline monooxygenase [N-oxide-forming] 3 isoform X1

      UniProtKB/TrEMBL
      A0A023JCQ5, F7HQX7
      Conserved Domains (1) summary
      pfam00743
      Location:2 → 532
      FMO-like; Flavin-binding monooxygenase-like

    3. XM_028850720.1 → XP_028706553.1  dimethylaniline monooxygenase [N-oxide-forming] 3 isoform X1

      UniProtKB/TrEMBL
      A0A023JCQ5, F7HQX7
      Conserved Domains (1) summary
      pfam00743
      Location:2 → 532
      FMO-like; Flavin-binding monooxygenase-like

    4. XM_015123224.2 → XP_014978710.1  dimethylaniline monooxygenase [N-oxide-forming] 3 isoform X1

      UniProtKB/TrEMBL
      A0A023JCQ5, F7HQX7
      Conserved Domains (1) summary
      pfam00743
      Location:2 → 532
      FMO-like; Flavin-binding monooxygenase-like

    5. XM_015123231.2 → XP_014978717.1  dimethylaniline monooxygenase [N-oxide-forming] 3 isoform X2

      UniProtKB/TrEMBL
      A0A023JCQ5
      Conserved Domains (2) summary
      pfam00743
      Location:5 → 492
      FMO-like; Flavin-binding monooxygenase-like
      cl21454
      Location:47 → 180
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SPQ7.3 GenPept UniProtKB/Swiss-Prot:Q8SPQ7

    Gene LinkOut

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