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    TP63 tumor protein p63 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 703997, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TP63provided by VGNC
    Official Full Name
    tumor protein p63provided by VGNC
    Primary source
    VGNC:VGNC:79000
    Locus tag
    EGK_12210
    See related
    Ensembl:ENSMMUG00000016466
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TP63 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (7950146..8223013, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (196352789..196617890)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene prolyl 3-hydroxylase 2 Neighboring gene S-methyl-5'-thioadenosine phosphorylase pseudogene Neighboring gene microRNA mir-944 Neighboring gene uncharacterized LOC114676210 Neighboring gene tumor protein p63 regulated 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein tetramerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tumor protein 63

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      7950146..8223013 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028843565.1 → XP_028699398.1  tumor protein 63 isoform X2

      UniProtKB/TrEMBL
      F7GBH1
      Conserved Domains (4) summary
      cd09572
      Location:542 → 606
      SAM_tumor-p63; SAM domain of tumor-p63 proteins
      pfam00870
      Location:162 → 357
      P53; P53 DNA-binding domain
      pfam07710
      Location:391 → 430
      P53_tetramer; P53 tetramerisation motif
      pfam08430
      Location:456 → 533
      Forkhead_N; Forkhead N-terminal region

    2. XM_015132502.2 → XP_014987988.1  tumor protein 63 isoform X4

      UniProtKB/TrEMBL
      F7GBH1
      Related
      ENSMMUP00000021634.4, ENSMMUT00000023126.4
      Conserved Domains (4) summary
      cd08367
      Location:160 → 341
      P53; P53 DNA-binding domain
      cd09572
      Location:526 → 590
      SAM_tumor-p63; SAM domain of tumor-p63 proteins
      pfam07710
      Location:375 → 411
      P53_tetramer; P53 tetramerisation motif
      pfam08430
      Location:440 → 517
      Forkhead_N; Forkhead N-terminal region

    3. XM_015132501.2 → XP_014987987.1  tumor protein 63 isoform X3

      UniProtKB/TrEMBL
      F7GBH1
      Conserved Domains (4) summary
      cd08367
      Location:177 → 358
      P53; P53 DNA-binding domain
      cd09572
      Location:539 → 603
      SAM_tumor-p63; SAM domain of tumor-p63 proteins
      pfam07710
      Location:388 → 424
      P53_tetramer; P53 tetramerisation motif
      pfam08430
      Location:453 → 530
      Forkhead_N; Forkhead N-terminal region

    4. XM_001092093.3 → XP_001092093.1  tumor protein 63 isoform X1

      See identical proteins and their annotated locations for XP_001092093.1

      UniProtKB/TrEMBL
      A0A5S6R9H3, A0A8J8YAQ1, F7FN64, F7GBH1, G7MK85
      Related
      ENSMMUP00000038274.3, ENSMMUT00000045252.3
      Conserved Domains (4) summary
      cd08367
      Location:177 → 358
      P53; P53 DNA-binding domain
      cd09572
      Location:543 → 607
      SAM_tumor-p63; SAM domain of tumor-p63 proteins
      pfam07710
      Location:392 → 428
      P53_tetramer; P53 tetramerisation motif
      pfam08430
      Location:457 → 534
      Forkhead_N; Forkhead N-terminal region

    5. XM_028843566.1 → XP_028699399.1  tumor protein 63 isoform X5

      UniProtKB/TrEMBL
      F7GBH1
      Conserved Domains (4) summary
      cd09572
      Location:504 → 568
      SAM_tumor-p63; SAM domain of tumor-p63 proteins
      pfam00870
      Location:124 → 319
      P53; P53 DNA-binding domain
      pfam07710
      Location:353 → 392
      P53_tetramer; P53 tetramerisation motif
      pfam08430
      Location:418 → 495
      Forkhead_N; Forkhead N-terminal region

    6. XM_028843567.1 → XP_028699400.1  tumor protein 63 isoform X7

      UniProtKB/TrEMBL
      F7FN69, H9ZEQ2
      Conserved Domains (3) summary
      cd08367
      Location:83 → 264
      P53; P53 DNA-binding domain
      cd09572
      Location:445 → 509
      SAM_tumor-p63; SAM domain of tumor-p63 proteins
      pfam07710
      Location:294 → 330
      P53_tetramer; P53 tetramerisation motif

    7. XM_001091977.4 → XP_001091977.3  tumor protein 63 isoform X6

      UniProtKB/TrEMBL
      F7FN69, F7GBG7
      Related
      ENSMMUP00000021636.4, ENSMMUT00000023128.4
      Conserved Domains (3) summary
      cd08367
      Location:83 → 264
      P53; P53 DNA-binding domain
      cd09572
      Location:449 → 513
      SAM_tumor-p63; SAM domain of tumor-p63 proteins
      pfam07710
      Location:298 → 334
      P53_tetramer; P53 tetramerisation motif

    8. XM_015132503.2 → XP_014987989.1  tumor protein 63 isoform X8

      UniProtKB/TrEMBL
      F7FN59
      Related
      ENSMMUP00000038275.3, ENSMMUT00000045253.3
      Conserved Domains (2) summary
      cd08367
      Location:177 → 358
      P53; P53 DNA-binding domain
      pfam07710
      Location:392 → 428
      P53_tetramer; P53 tetramerisation motif

    9. XM_015132504.2 → XP_014987990.2  tumor protein 63 isoform X9

      Conserved Domains (2) summary
      cd08367
      Location:83 → 264
      P53; P53 DNA-binding domain
      pfam07710
      Location:298 → 334
      P53_tetramer; P53 tetramerisation motif
    Nucleotide Protein
    Heading Accession and Version

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