U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    PLXNA4 plexin A4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 705098, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    PLXNA4provided by VGNC
    Official Full Name
    plexin A4provided by VGNC
    Primary source
    VGNC:VGNC:76186
    See related
    Ensembl:ENSMMUG00000005127
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PLXNA4 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (158450403..158900150, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (158285205..158731608, complement)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene F-actin-capping protein subunit alpha-1-like Neighboring gene uncharacterized LOC106997670 Neighboring gene uncharacterized LOC106997671 Neighboring gene small nucleolar RNA SNORD46 Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 3

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables semaphorin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of axonogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell shape IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in semaphorin-plexin signaling pathway involved in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of semaphorin receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    plexin-A4

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      158450403..158900150 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028846301.1 → XP_028702134.1  plexin-A4 isoform X2

      UniProtKB/TrEMBL
      G7MME3
      Conserved Domains (8) summary
      cd11274
      Location:39 → 511
      Sema_plexin_A4; The Sema domain, a protein interacting module, of Plexin A4
      smart00423
      Location:510 → 548
      PSI; domain found in Plexins, Semaphorins and Integrins
      cd00603
      Location:1046 → 1126
      IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
      cd01179
      Location:859 → 942
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01181
      Location:944 → 1044
      IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      pfam01437
      Location:655 → 693
      PSI; Plexin repeat
      pfam08337
      Location:1215 → 1768
      Plexin_cytopl; Plexin cytoplasmic RasGAP domain
      cl15674
      Location:765 → 857
      IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...

    2. XM_015134941.2 → XP_014990427.1  plexin-A4 isoform X1

      UniProtKB/TrEMBL
      F7BXM1, G7MME3
      Related
      ENSMMUP00000006793.3, ENSMMUT00000007228.4
      Conserved Domains (10) summary
      cd11274
      Location:39 → 511
      Sema_plexin_A4; The Sema domain, a protein interacting module, of Plexin A4
      smart00423
      Location:510 → 548
      PSI; domain found in Plexins, Semaphorins and Integrins
      cd00603
      Location:1142 → 1222
      IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
      cd01179
      Location:955 → 1038
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01180
      Location:858 → 953
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01181
      Location:1040 → 1140
      IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      pfam01437
      Location:804 → 856
      PSI; Plexin repeat
      pfam08337
      Location:1311 → 1864
      Plexin_cytopl; Plexin cytoplasmic RasGAP domain
      pfam17960
      Location:564 → 654
      TIG_plexin; TIG domain
      pfam18020
      Location:708 → 802
      TIG_2; TIG domain found in plexin
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials