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    PLXNA1 plexin A1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 716805, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PLXNA1provided by VGNC
    Official Full Name
    plexin A1provided by VGNC
    Primary source
    VGNC:VGNC:76183
    Locus tag
    EGK_11398
    See related
    Ensembl:ENSMMUG00000016720
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PLXNA1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (149470862..149520705, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (48102553..48152464)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene putative uncharacterized protein C3orf56 Neighboring gene putative uncharacterized protein C3orf56 Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 6 Neighboring gene protein RCC2 pseudogene Neighboring gene uncharacterized LOC114676158

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables semaphorin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of axonogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell shape IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in semaphorin-plexin signaling pathway involved in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of semaphorin receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    plexin-A1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      149470862..149520705 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001114446.4 → XP_001114446.3  plexin-A1

      UniProtKB/TrEMBL
      G7MKN5
      Related
      ENSMMUP00000060049.2, ENSMMUT00000064380.2
      Conserved Domains (9) summary
      cd11271
      Location:57 → 532
      Sema_plexin_A1; The Sema domain, a protein interacting module, of Plexin A1
      cd01179
      Location:980 → 1065
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01180
      Location:883 → 979
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01181
      Location:1067 → 1167
      IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      pfam01437
      Location:533 → 575
      PSI; Plexin repeat
      pfam01833
      Location:1169 → 1253
      TIG; IPT/TIG domain
      pfam08337
      Location:1337 → 1885
      Plexin_cytopl; Plexin cytoplasmic RasGAP domain
      pfam17960
      Location:588 → 678
      TIG_plexin; TIG domain
      pfam18020
      Location:732 → 826
      TIG_2; TIG domain found in plexin
    Nucleotide Protein
    Heading Accession and Version

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