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    PCSK7 proprotein convertase subtilisin/kexin type 7 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 697567, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PCSK7provided by VGNC
    Official Full Name
    proprotein convertase subtilisin/kexin type 7provided by VGNC
    Primary source
    VGNC:VGNC:75788
    See related
    Ensembl:ENSMMUG00000002061
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PCSK7 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (110267113..110294241, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (110037057..110064980, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114672412 Neighboring gene SID1 transmembrane family member 2 Neighboring gene uncharacterized LOC114672413 Neighboring gene transgelin Neighboring gene ring finger protein 214 Neighboring gene uncharacterized LOC100429897 Neighboring gene beta-secretase 1 Neighboring gene centrosomal protein 164

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in trans-Golgi network IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    proprotein convertase subtilisin/kexin type 7
    Names
    proprotein convertase subtilisin/kexin type 7 preproprotein
    XP_014971267.2
    XP_028689851.1
    XP_028689852.1
    XP_028689853.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      110267113..110294241 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015115781.2 → XP_014971267.2  proprotein convertase subtilisin/kexin type 7

      UniProtKB/TrEMBL
      F6WWR1, H9ZF79
      Related
      ENSMMUP00000002761.4, ENSMMUT00000002921.4
      Conserved Domains (3) summary
      cd04059
      Location:145 → 440
      Peptidases_S8_Protein_convertases_Kexins_Furin-lik; Peptidase S8 family domain in Protein convertases
      pfam01483
      Location:525 → 612
      P_proprotein; Proprotein convertase P-domain
      pfam16470
      Location:53 → 141
      S8_pro-domain; Peptidase S8 pro-domain

    2. XM_028834020.1 → XP_028689853.1  proprotein convertase subtilisin/kexin type 7

      UniProtKB/TrEMBL
      F6WWR1, H9ZF79
      Related
      ENSMMUP00000073738.1, ENSMMUT00000106605.1
      Conserved Domains (3) summary
      cd04059
      Location:145 → 440
      Peptidases_S8_Protein_convertases_Kexins_Furin-lik; Peptidase S8 family domain in Protein convertases
      pfam01483
      Location:525 → 612
      P_proprotein; Proprotein convertase P-domain
      pfam16470
      Location:53 → 141
      S8_pro-domain; Peptidase S8 pro-domain

    3. XM_028834018.1 → XP_028689851.1  proprotein convertase subtilisin/kexin type 7

      UniProtKB/TrEMBL
      F6WWR1, H9ZF79
      Related
      ENSMMUP00000078604.1, ENSMMUT00000109934.1
      Conserved Domains (3) summary
      cd04059
      Location:145 → 440
      Peptidases_S8_Protein_convertases_Kexins_Furin-lik; Peptidase S8 family domain in Protein convertases
      pfam01483
      Location:525 → 612
      P_proprotein; Proprotein convertase P-domain
      pfam16470
      Location:53 → 141
      S8_pro-domain; Peptidase S8 pro-domain

    4. XM_028834019.1 → XP_028689852.1  proprotein convertase subtilisin/kexin type 7

      UniProtKB/TrEMBL
      F6WWR1, H9ZF79
      Conserved Domains (3) summary
      cd04059
      Location:145 → 440
      Peptidases_S8_Protein_convertases_Kexins_Furin-lik; Peptidase S8 family domain in Protein convertases
      pfam01483
      Location:525 → 612
      P_proprotein; Proprotein convertase P-domain
      pfam16470
      Location:53 → 141
      S8_pro-domain; Peptidase S8 pro-domain

    RNA

    1. XR_003722777.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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