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    ADGRE2 adhesion G protein-coupled receptor E2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 654420, updated on 5-Mar-2024

    Summary

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    Gene symbol
    ADGRE2
    Gene description
    adhesion G protein-coupled receptor E2
    See related
    Ensembl:ENSMMUG00000018932
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    EMR2
    Orthologs
    human all
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    Genomic context

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    See ADGRE2 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (14368627..14412439, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (14712150..14725494) , (14800425..14803067)

    Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene adhesion G protein-coupled receptor E3 Neighboring gene zinc finger protein 333 Neighboring gene olfactory receptor 7A10 Neighboring gene olfactory receptor family 7 subfamily C member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An unusual mode of concerted evolution of the EGF-TM7 receptor chimera EMR2. Kwakkenbos MJ, et al. FASEB J, 2006 Dec. PMID 17068111
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    adhesion G protein-coupled receptor E2
    Names
    EGF-like module receptor 2
    EGF-like module-containing mucin-like hormone receptor-like 2
    egf-like module containing, mucin-like, hormone receptor-like 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001038662.1 → NP_001033751.1  adhesion G protein-coupled receptor E2 precursor

      See identical proteins and their annotated locations for NP_001033751.1

      Status: PROVISIONAL

      Source sequence(s)
      DQ227271
      UniProtKB/Swiss-Prot
      Q2Q426
      UniProtKB/TrEMBL
      A0A1D5QWX1
      Related
      ENSMMUP00000052551.2, ENSMMUT00000057396.2
      Conserved Domains (5) summary
      smart00303
      Location:472 → 522
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00179
      Location:116 → 148
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:64 → 99
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:160 → 198
      EGF_CA; Calcium-binding EGF domain
      cl21561
      Location:526 → 767
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041772.1 Reference Mmul_10 Primary Assembly

      Range
      14368627..14412439 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028838331.1 → XP_028694164.1  adhesion G protein-coupled receptor E2 isoform X2

      UniProtKB/TrEMBL
      A0A1D5QWX1, A0A5F8A8D4
      Related
      ENSMMUP00000073181.1, ENSMMUT00000108223.1
      Conserved Domains (6) summary
      smart00303
      Location:472 → 522
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00179
      Location:116 → 148
      EGF_CA; Calcium-binding EGF-like domain
      pfam07645
      Location:160 → 198
      EGF_CA; Calcium-binding EGF domain
      pfam12662
      Location:88 → 119
      cEGF; Complement Clr-like EGF-like
      cd14964
      Location:529 → 553
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:526 → 788
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    2. XM_028838333.1 → XP_028694166.1  adhesion G protein-coupled receptor E2 isoform X3

      UniProtKB/TrEMBL
      A0A1D5QWX1
      Conserved Domains (7) summary
      smart00303
      Location:423 → 473
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00179
      Location:64 → 98
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:116 → 151
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:160 → 195
      EGF_CA; Calcium-binding EGF domain
      pfam12662
      Location:88 → 119
      cEGF; Complement Clr-like EGF-like
      cd14964
      Location:480 → 504
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:477 → 739
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    3. XM_028838330.1 → XP_028694163.1  adhesion G protein-coupled receptor E2 isoform X1

      UniProtKB/TrEMBL
      A0A1D5QWX1
      Conserved Domains (7) summary
      smart00303
      Location:472 → 522
      GPS; G-protein-coupled receptor proteolytic site domain
      smart00179
      Location:64 → 98
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:116 → 151
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:160 → 198
      EGF_CA; Calcium-binding EGF domain
      pfam12662
      Location:88 → 119
      cEGF; Complement Clr-like EGF-like
      cd14964
      Location:529 → 553
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:526 → 788
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2Q426.1 GenPept UniProtKB/Swiss-Prot:Q2Q426

    Gene LinkOut

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