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    KLF4 KLF transcription factor 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 711169, updated on 17-Aug-2024

    Summary

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    Official Symbol
    KLF4provided by VGNC
    Official Full Name
    KLF transcription factor 4provided by VGNC
    Primary source
    VGNC:VGNC:74029
    See related
    Ensembl:ENSMMUG00000006088
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See KLF4 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (35397811..35402749)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 15 NC_027907.1 (32064318..32067563)

    Chromosome 15 - NC_041768.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC106993658 Neighboring gene U6 spliceosomal RNA Neighboring gene RAD23 homolog B, nucleotide excision repair protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Generation of induced pluripotent stem cells from adult rhesus monkey fibroblasts. Liu H, et al. Cell Stem Cell, 2008 Dec 4. PMID 19041774
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Krueppel-like factor 4
    Names
    Kruppel like factor 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001142793.2 → NP_001136265.1  Krueppel-like factor 4

      See identical proteins and their annotated locations for NP_001136265.1

      Status: VALIDATED

      Source sequence(s)
      FJ375752, JV727062, JV727063
      UniProtKB/TrEMBL
      B8XIA4, F6VVB3, G7NEK6
      Related
      ENSMMUP00000007996.3, ENSMMUT00000008508.4
      Conserved Domains (4) summary
      COG5048
      Location:391 → 474
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:398 → 420
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:442 → 467
      zf-H2C2_2; Zinc-finger double domain
      cd21582
      Location:7 → 396
      KLF4_N; N-terminal domain of Kruppel-like factor 4

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041768.1 Reference Mmul_10 Primary Assembly

      Range
      35397811..35402749
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028834359.1 → XP_028690192.1  Krueppel-like factor 4 isoform X1

      UniProtKB/TrEMBL
      G7NEK6
      Conserved Domains (3) summary
      COG5048
      Location:424 → 507
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:431 → 453
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:475 → 500
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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