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    YTHDC2 YTH N6-methyladenosine RNA binding protein C2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 694612, updated on 17-Aug-2024

    Summary

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    Official Symbol
    YTHDC2provided by VGNC
    Official Full Name
    YTH N6-methyladenosine RNA binding protein C2provided by VGNC
    Primary source
    VGNC:VGNC:79452
    See related
    Ensembl:ENSMMUG00000001376
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See YTHDC2 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (111037711..111118035)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (110945529..111026350)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene MCC regulator of WNT signaling pathway Neighboring gene U4atac minor spliceosomal RNA Neighboring gene testis specific serine kinase 1B Neighboring gene potassium calcium-activated channel subfamily N member 2 Neighboring gene uncharacterized LOC106998891

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in intracellular anatomical structure IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    probable ATP-dependent RNA helicase YTHDC2; 3'-5' RNA helicase YTHDC2
    Names
    YTH domain containing 2
    putative ATP-dependent RNA helicase YTHDC2
    XP_028705493.1
    XP_028705494.1
    XP_028705495.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      111037711..111118035
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028849661.1 → XP_028705494.1  3'-5' RNA helicase YTHDC2 isoform X2

      UniProtKB/TrEMBL
      H9F9F5
      Conserved Domains (5) summary
      COG1643
      Location:27 → 854
      HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
      sd00045
      Location:343 → 375
      ANK; ANK repeat [structural motif]
      pfam04146
      Location:1126 → 1257
      YTH; YT521-B-like domain
      pfam07717
      Location:809 → 904
      OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold
      cd17987
      Location:31 → 206
      DEXHc_YTHDC2; DEXH-box helicase domain of YTH domain containing 2

    2. XM_028849662.1 → XP_028705495.1  3'-5' RNA helicase YTHDC2 isoform X3

      UniProtKB/TrEMBL
      H9F9F5
      Conserved Domains (6) summary
      COG0666
      Location:189 → 273
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      COG1643
      Location:318 → 716
      HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
      sd00045
      Location:205 → 237
      ANK; ANK repeat [structural motif]
      pfam04146
      Location:988 → 1119
      YTH; YT521-B-like domain
      pfam07717
      Location:671 → 766
      OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold
      cl28899
      Location:1 → 68
      DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily

    3. XM_028849660.1 → XP_028705493.1  3'-5' RNA helicase YTHDC2 isoform X1

      UniProtKB/TrEMBL
      F7D614, G7MVJ8
      Related
      ENSMMUP00000001834.4, ENSMMUT00000001947.4
      Conserved Domains (6) summary
      cd06007
      Location:46 → 104
      R3H_DEXH_helicase; R3H domain of a group of proteins which also contain a DEXH-box helicase domain, and may function as ATP-dependent DNA or RNA helicases. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine ...
      COG1643
      Location:189 → 1016
      HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
      sd00045
      Location:505 → 537
      ANK; ANK repeat [structural motif]
      pfam04146
      Location:1288 → 1419
      YTH; YT521-B-like domain
      pfam07717
      Location:971 → 1066
      OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold
      cd17987
      Location:193 → 368
      DEXHc_YTHDC2; DEXH-box helicase domain of YTH domain containing 2
    Nucleotide Protein
    Heading Accession and Version

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