RET ret proto-oncogene [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: RETprovided by VGNC
Official Full Name: ret proto-oncogeneprovided by VGNC
Primary source: VGNC:VGNC:76899
See related: Ensembl:ENSMMUG00000015400
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 20

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	9	NC_041762.1 (43802318..43855382)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	9	NC_027901.1 (38485064..38538082)

Chromosome 9 - NC_041762.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

STS-T15350 (e-PCR)
- UniSTS:15110

GDB:579598 (e-PCR)
- UniSTS:157821

GDB:281473 (e-PCR)
- UniSTS:156383

GDB:342177 (e-PCR)
- UniSTS:156641

GDB:592843 (e-PCR)
- UniSTS:157925

G59921 (e-PCR)
- UniSTS:137202

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables calcium ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables transmembrane receptor protein tyrosine kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in homophilic cell adhesion via plasma membrane adhesion molecules	IEA Inferred from Electronic Annotation more info	PubMed
involved_in multicellular organism development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of kinase activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in axon	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed
part_of receptor complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: proto-oncogene tyrosine-protein kinase receptor Ret

XP_015002368.1

EC 2.7.10.1

EC 3.4.21.59

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041762.1 Reference Mmul_10 Primary Assembly

Range

43802318..43855382

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015146882.2 → XP_015002368.1 proto-oncogene tyrosine-protein kinase receptor Ret

UniProtKB/TrEMBL

F6S299, H9ZBZ9

Related

ENSMMUP00000020196.4, ENSMMUT00000021592.4

Conserved Domains (3) summary

cd05045
Location:724 → 1013

PTKc_RET; Catalytic domain of the Protein Tyrosine Kinase, REarranged during Transfection protein

pfam00028
Location:173 → 262

Cadherin; Cadherin domain

pfam07714
Location:725 → 1006

Pkinase_Tyr; Protein tyrosine kinase