U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    PROS1 protein S [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 694845, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    PROS1provided by VGNC
    Official Full Name
    protein Sprovided by VGNC
    Primary source
    VGNC:VGNC:76426
    See related
    Ensembl:ENSMMUG00000020334
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PROS1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (181868867..181970301)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (14911703..15014376, complement)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene ADP ribosylation factor like GTPase 13B Neighboring gene non-histone chromosomal protein HMG-14 pseudogene Neighboring gene U6 spliceosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene small nucleolar RNA U3

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Identification of candidate residues for interaction of protein S with C4b binding protein and activated protein C. Greengard JS, et al. Biochem J, 1995 Jan 15. PMID 7832752, Free PMC Article
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    vitamin K-dependent protein S
    Names
    protein S (alpha)
    vitamin K-dependent protein S preproprotein

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044726.1 → NP_001038191.1  vitamin K-dependent protein S

      See identical proteins and their annotated locations for NP_001038191.1

      Status: PROVISIONAL

      Source sequence(s)
      L31380
      UniProtKB/TrEMBL
      F6WGA0
      Related
      ENSMMUP00000026760.4, ENSMMUT00000028601.4
      Conserved Domains (8) summary
      smart00069
      Location:2 → 41
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
      cd00054
      Location:75 → 111
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00054
      Location:285 → 415
      Laminin_G_1; Laminin G domain
      pfam02210
      Location:470 → 603
      Laminin_G_2; Laminin G domain
      pfam06247
      Location:90 → 249
      Plasmod_Pvs28; Plasmodium ookinete surface protein Pvs28
      pfam07645
      Location:157 → 197
      EGF_CA; Calcium-binding EGF domain
      pfam14670
      Location:124 → 155
      FXa_inhibition; Coagulation Factor Xa inhibitory site
      cl00057
      Location:191 → 237
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      181868867..181970301
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015128567.2 → XP_014984053.1  vitamin K-dependent protein S isoform X1

      UniProtKB/TrEMBL
      F6WG91, G7MJU4
      Related
      ENSMMUP00000026761.3, ENSMMUT00000028602.4
      Conserved Domains (6) summary
      smart00069
      Location:23 → 85
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
      smart00282
      Location:509 → 647
      LamG; Laminin G domain
      cd00054
      Location:119 → 155
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:201 → 241
      EGF_CA; Calcium-binding EGF domain
      pfam00054
      Location:329 → 459
      Laminin_G_1; Laminin G domain
      pfam14670
      Location:168 → 199
      FXa_inhibition; Coagulation Factor Xa inhibitory site

    2. XM_028843093.1 → XP_028698926.1  vitamin K-dependent protein S isoform X2

      UniProtKB/Swiss-Prot
      Q28520
      Conserved Domains (6) summary
      smart00069
      Location:7 → 65
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
      cd00054
      Location:99 → 135
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam02210
      Location:494 → 627
      Laminin_G_2; Laminin G domain
      pfam07645
      Location:181 → 221
      EGF_CA; Calcium-binding EGF domain
      pfam00054
      Location:309 → 439
      Laminin_G_1; Laminin G domain
      pfam14670
      Location:148 → 179
      FXa_inhibition; Coagulation Factor Xa inhibitory site
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q28520.2 GenPept UniProtKB/Swiss-Prot:Q28520

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials