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    AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 714140, updated on 17-Aug-2024

    Summary

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    Official Symbol
    AGAP3provided by VGNC
    Official Full Name
    ArfGAP with GTPase domain, ankyrin repeat and PH domain 3provided by VGNC
    Primary source
    VGNC:VGNC:69621
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See AGAP3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (177089081..177145799)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (177308227..177365307)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 4 member 2 Neighboring gene Fas activated serine/threonine kinase Neighboring gene transmembrane and ubiquitin like domain containing 1 Neighboring gene gastrulation brain homeobox 1 Neighboring gene ankyrin repeat and SOCS box containing 10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      177089081..177145799
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028846482.1 → XP_028702315.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X7

      Conserved Domains (4) summary
      cd01250
      Location:55 → 299
      PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
      sd00045
      Location:443 → 473
      ANK; ANK repeat [structural motif]
      cd08855
      Location:315 → 424
      ArfGap_AGAP3; ArfGAP with GTPase domain, ANK repeat and PH domain 3
      pfam12796
      Location:443 → 533
      Ank_2; Ankyrin repeats (3 copies)

    2. XM_015135298.2 → XP_014990784.2  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X9

      Conserved Domains (1) summary
      cd04103
      Location:129 → 286
      Centaurin_gamma; Centaurin gamma (CENTG) GTPase

    3. XM_015135299.2 → XP_014990785.2  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X10

      Conserved Domains (1) summary
      cd04103
      Location:129 → 286
      Centaurin_gamma; Centaurin gamma (CENTG) GTPase

    4. XM_028846480.1 → XP_028702313.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X5

      UniProtKB/TrEMBL
      G7MNH0
      Conserved Domains (5) summary
      cd04103
      Location:129 → 286
      Centaurin_gamma; Centaurin gamma (CENTG) GTPase
      cd01250
      Location:402 → 543
      PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
      sd00045
      Location:687 → 717
      ANK; ANK repeat [structural motif]
      cd08855
      Location:559 → 668
      ArfGap_AGAP3; ArfGAP with GTPase domain, ANK repeat and PH domain 3
      pfam12796
      Location:687 → 777
      Ank_2; Ankyrin repeats (3 copies)

    5. XM_015135295.2 → XP_014990781.2  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X2

      UniProtKB/TrEMBL
      G7MNH0
      Conserved Domains (5) summary
      cd04103
      Location:129 → 286
      Centaurin_gamma; Centaurin gamma (CENTG) GTPase
      cd01250
      Location:402 → 646
      PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
      sd00045
      Location:790 → 820
      ANK; ANK repeat [structural motif]
      cd08855
      Location:662 → 771
      ArfGap_AGAP3; ArfGAP with GTPase domain, ANK repeat and PH domain 3
      pfam12796
      Location:790 → 880
      Ank_2; Ankyrin repeats (3 copies)

    6. XM_028846481.1 → XP_028702314.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X6

      Conserved Domains (1) summary
      cd04103
      Location:308 → 465
      Centaurin_gamma; Centaurin gamma (CENTG) GTPase

    7. XM_028846477.1 → XP_028702310.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X1

      UniProtKB/TrEMBL
      G7MNH0
      Conserved Domains (5) summary
      cd01250
      Location:173 → 417
      PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
      sd00045
      Location:561 → 591
      ANK; ANK repeat [structural motif]
      cd08855
      Location:433 → 542
      ArfGap_AGAP3; ArfGAP with GTPase domain, ANK repeat and PH domain 3
      pfam12796
      Location:561 → 651
      Ank_2; Ankyrin repeats (3 copies)
      cl38936
      Location:1 → 57
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    8. XM_028846478.1 → XP_028702311.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X3

      Conserved Domains (5) summary
      cd01250
      Location:173 → 360
      PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
      sd00045
      Location:504 → 534
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:504 → 594
      Ank_2; Ankyrin repeats (3 copies)
      cd08855
      Location:376 → 485
      ArfGap_AGAP3; ArfGAP with GTPase domain, ANK repeat and PH domain 3
      cl21455
      Location:1 → 57
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    9. XM_028846479.1 → XP_028702312.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X4

      Conserved Domains (5) summary
      cd01250
      Location:173 → 314
      PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
      sd00045
      Location:458 → 488
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:458 → 548
      Ank_2; Ankyrin repeats (3 copies)
      cd08855
      Location:330 → 439
      ArfGap_AGAP3; ArfGAP with GTPase domain, ANK repeat and PH domain 3
      cl21455
      Location:1 → 57
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    10. XM_028846483.1 → XP_028702316.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X8

      Conserved Domains (4) summary
      cd01250
      Location:55 → 196
      PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
      sd00045
      Location:340 → 370
      ANK; ANK repeat [structural motif]
      cd08855
      Location:212 → 321
      ArfGap_AGAP3; ArfGAP with GTPase domain, ANK repeat and PH domain 3
      pfam12796
      Location:340 → 430
      Ank_2; Ankyrin repeats (3 copies)
    Nucleotide Protein
    Heading Accession and Version

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