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    MAOA monoamine oxidase A [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 708371, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MAOAprovided by VGNC
    Official Full Name
    monoamine oxidase Aprovided by VGNC
    Primary source
    VGNC:VGNC:74487
    See related
    Ensembl:ENSMMUG00000019489
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MAOA in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (43576151..43661380)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (43706159..43835878)

    Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene homeobox protein NANOG pseudogene Neighboring gene uncharacterized LOC114675139 Neighboring gene monoamine oxidase B Neighboring gene norrin cystine knot growth factor NDP

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Peer social interaction is facilitated in juvenile rhesus monkeys treated with fluoxetine. Golub MS, et al. Neuropharmacology, 2016 Jun. PMID 26905291, Free PMC Article
    2. MAOA expression predicts vulnerability for alcohol use. Cervera-Juanes R, et al. Mol Psychiatry, 2016 Apr. PMID 26148813, Free PMC Article
    3. Sleep patterns in male juvenile monkeys are influenced by gestational iron deprivation and monoamine oxidase A genotype. Golub MS, et al. Br J Nutr, 2014 Nov 14. PMID 25351859, Free PMC Article
    4. Influence of prenatal iron deficiency and MAOA genotype on response to social challenge in rhesus monkey infants. Golub MS, et al. Genes Brain Behav, 2012 Apr. PMID 22340208, Free PMC Article
    5. What is an "adverse" environment? Interactions of rearing experiences and MAOA genotype in rhesus monkeys. Karere GM, et al. Biol Psychiatry, 2009 May 1. PMID 19103441, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Social behavior was facilitated by chronic fluoxetine treatment in juvenile rhesus monkeys interacting with a familiar peer. The type of social behavior affected depended on the MAOA genotype of the monkey and its partner.
      Title: Peer social interaction is facilitated in juvenile rhesus monkeys treated with fluoxetine.
    2. Results provide novel evidence that blood MAOA expression predicts alcohol consumption and that heavy alcohol use is linked to low MAOA expression in both the blood and NAc core.
      Title: MAOA expression predicts vulnerability for alcohol use.
    3. study found the ability to consolidate sleep during the dark cycle was disrupted by prenatal iron deprivation, specifically in monkeys with the low-MAOA genotype
      Title: Sleep patterns in male juvenile monkeys are influenced by gestational iron deprivation and monoamine oxidase A genotype.
    4. The effects of iron deficiency are dependent on MAOA genotype in terms of both direction and size of the effect.
      Title: Influence of prenatal iron deficiency and MAOA genotype on response to social challenge in rhesus monkey infants.
    5. rhMAOA-LPR allele modifies the effects of maternal temperament on offspring's personality development.
      Title: Similarity in temperament between mother and offspring rhesus monkeys: sex differences and the role of monoamine oxidase-a and serotonin transporter promoter polymorphism genotypes.
    6. Among mother-reared animals, broader contextual features, associated with the social environment and experience of the mother, can affect the extent to which genotype contributes to behavioral expression under conditions of challenge.
      Title: What is an "adverse" environment? Interactions of rearing experiences and MAOA genotype in rhesus monkeys.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    amine oxidase [flavin-containing] A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041774.1 Reference Mmul_10 Primary Assembly

      Range
      43576151..43661380
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015127229.2 → XP_014982715.1  amine oxidase [flavin-containing] A

      UniProtKB/TrEMBL
      A0A5F8ASS5, F7D3I3
      Related
      ENSMMUP00000025612.4, ENSMMUT00000027384.4
      Conserved Domains (5) summary
      COG1231
      Location:457 → 902
      YobN; Monoamine oxidase [Amino acid transport and metabolism]
      pfam11235
      Location:273 → 434
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      pfam13450
      Location:460 → 526
      NAD_binding_8; NAD(P)-binding Rossmann-like domain
      pfam15352
      Location:212 → 365
      K1377; Susceptibility to monomelic amyotrophy
      cl21454
      Location:432 → 485
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    Nucleotide Protein
    Heading Accession and Version

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