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    APH1B aph-1 homolog B, gamma-secretase subunit [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 705718, updated on 17-Aug-2024

    Summary

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    Official Symbol
    APH1Bprovided by VGNC
    Official Full Name
    aph-1 homolog B, gamma-secretase subunitprovided by VGNC
    Primary source
    VGNC:VGNC:69891
    See related
    Ensembl:ENSMMUG00000059755
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See APH1B in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (39722355..39751415)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (39862143..39891226)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S27 like Neighboring gene RAB8B, member RAS oncogene family Neighboring gene uncharacterized LOC114679424 Neighboring gene carbonic anhydrase 12 Neighboring gene ubiquitin specific peptidase 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein-macromolecule adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Notch receptor processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of gamma-secretase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    gamma-secretase subunit APH-1B
    Names
    anterior pharynx defective 1 homolog B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      39722355..39751415
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001105067.4 → XP_001105067.2  gamma-secretase subunit APH-1B isoform X1

      UniProtKB/TrEMBL
      F7DK04, G7MXS4, H9G0E6
      Related
      ENSMMUP00000075184.1, ENSMMUT00000087122.1
      Conserved Domains (1) summary
      pfam06105
      Location:3 → 232
      Aph-1; Aph-1 protein

    2. XM_028851016.1 → XP_028706849.1  gamma-secretase subunit APH-1B isoform X2

      Conserved Domains (1) summary
      pfam06105
      Location:3 → 186
      Aph-1; Aph-1 protein
    Nucleotide Protein
    Heading Accession and Version

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