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    ME1 malic enzyme 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 694739, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ME1provided by VGNC
    Official Full Name
    malic enzyme 1provided by VGNC
    Primary source
    VGNC:VGNC:74694
    Locus tag
    EGK_15118
    See related
    Ensembl:ENSMMUG00000012592
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ME1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (89662256..89890378)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (81394270..81623742, complement)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene cytochrome c, somatic pseudogene Neighboring gene serine protease 35 Neighboring gene uncharacterized LOC114677554 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene RWD domain containing 2A Neighboring gene phosphoglucomutase 3 Neighboring gene DOP1 leucine zipper like protein A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables malate dehydrogenase (decarboxylating) (NAD+) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables malate dehydrogenase (decarboxylating) (NADP+) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in malate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in pyruvate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    NADP-dependent malic enzyme

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      89662256..89890378
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015136858.2 → XP_014992344.1  NADP-dependent malic enzyme

      UniProtKB/TrEMBL
      A0A5F8AFZ9, A0A663DET9, A0A8J8YS82, F7FDW2, G7MPT7
      Related
      ENSMMUP00000016529.3, ENSMMUT00000017651.4
      Conserved Domains (3) summary
      cd05312
      Location:270 → 547
      NAD_bind_1_malic_enz; NAD(P) binding domain of malic enzyme (ME), subgroup 1
      PLN03129
      Location:11 → 551
      PLN03129; NADP-dependent malic enzyme; Provisional
      pfam00390
      Location:79 → 260
      malic; Malic enzyme, N-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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