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    FLCN folliculin [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 698082, updated on 17-Aug-2024

    Summary

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    Official Symbol
    FLCNprovided by VGNC
    Official Full Name
    folliculinprovided by VGNC
    Primary source
    VGNC:VGNC:97770
    See related
    Ensembl:ENSMMUG00000013345
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See FLCN in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (17035387..17061963, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (17345343..17369648, complement)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene myosin phosphatase Rho interacting protein Neighboring gene U6 spliceosomal RNA Neighboring gene phospholipase D family member 6 Neighboring gene actin-85C-like Neighboring gene COP9 signalosome subunit 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of TORC1 signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transforming growth factor beta receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    folliculin
    NP_001253620.1
    XP_014974152.1
    XP_014974154.1
    XP_014974155.1
    XP_014974156.1
    XP_014974157.1
    XP_028691316.1
    XP_028691317.1
    XP_028691318.1
    XP_028691319.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266691.1 → NP_001253620.1  folliculin

      See identical proteins and their annotated locations for NP_001253620.1

      Status: PROVISIONAL

      Source sequence(s)
      JV043269
      UniProtKB/TrEMBL
      F6XBF6, G7NJ12, H9ERY6
      Related
      ENSMMUP00000017544.2, ENSMMUT00000018731.3
      Conserved Domains (2) summary
      pfam11704
      Location:106 → 265
      Folliculin; Vesicle coat protein involved in Golgi to plasma membrane transport
      pfam16692
      Location:344 → 566
      Folliculin_C; Folliculin C-terminal domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      17035387..17061963 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028835483.1 → XP_028691316.1  folliculin isoform X1

      UniProtKB/TrEMBL
      F6XBF6, G7NJ12, H9ERY6
      Related
      ENSMMUP00000075815.1, ENSMMUT00000085426.1
      Conserved Domains (2) summary
      pfam11704
      Location:106 → 265
      Folliculin; Vesicle coat protein involved in Golgi to plasma membrane transport
      pfam16692
      Location:344 → 566
      Folliculin_C; Folliculin C-terminal domain

    2. XM_015118670.2 → XP_014974156.1  folliculin isoform X2

      UniProtKB/TrEMBL
      G7NJ12
      Conserved Domains (2) summary
      pfam11704
      Location:25 → 184
      Folliculin; Vesicle coat protein involved in Golgi to plasma membrane transport
      pfam16692
      Location:263 → 485
      Folliculin_C; Folliculin C-terminal domain

    3. XM_015118671.2 → XP_014974157.1  folliculin isoform X1

      UniProtKB/TrEMBL
      F6XBF6, G7NJ12, H9ERY6
      Conserved Domains (2) summary
      pfam11704
      Location:106 → 265
      Folliculin; Vesicle coat protein involved in Golgi to plasma membrane transport
      pfam16692
      Location:344 → 566
      Folliculin_C; Folliculin C-terminal domain

    4. XM_015118668.2 → XP_014974154.1  folliculin isoform X1

      UniProtKB/TrEMBL
      F6XBF6, G7NJ12, H9ERY6
      Conserved Domains (2) summary
      pfam11704
      Location:106 → 265
      Folliculin; Vesicle coat protein involved in Golgi to plasma membrane transport
      pfam16692
      Location:344 → 566
      Folliculin_C; Folliculin C-terminal domain

    5. XM_028835484.1 → XP_028691317.1  folliculin isoform X1

      UniProtKB/TrEMBL
      F6XBF6, G7NJ12, H9ERY6
      Conserved Domains (2) summary
      pfam11704
      Location:106 → 265
      Folliculin; Vesicle coat protein involved in Golgi to plasma membrane transport
      pfam16692
      Location:344 → 566
      Folliculin_C; Folliculin C-terminal domain

    6. XM_028835486.1 → XP_028691319.1  folliculin isoform X1

      UniProtKB/TrEMBL
      F6XBF6, G7NJ12, H9ERY6
      Related
      ENSMMUP00000071602.1, ENSMMUT00000109572.1
      Conserved Domains (2) summary
      pfam11704
      Location:106 → 265
      Folliculin; Vesicle coat protein involved in Golgi to plasma membrane transport
      pfam16692
      Location:344 → 566
      Folliculin_C; Folliculin C-terminal domain

    7. XM_015118666.2 → XP_014974152.1  folliculin isoform X1

      UniProtKB/TrEMBL
      F6XBF6, G7NJ12, H9ERY6
      Conserved Domains (2) summary
      pfam11704
      Location:106 → 265
      Folliculin; Vesicle coat protein involved in Golgi to plasma membrane transport
      pfam16692
      Location:344 → 566
      Folliculin_C; Folliculin C-terminal domain

    8. XM_015118669.2 → XP_014974155.1  folliculin isoform X1

      UniProtKB/TrEMBL
      F6XBF6, G7NJ12, H9ERY6
      Conserved Domains (2) summary
      pfam11704
      Location:106 → 265
      Folliculin; Vesicle coat protein involved in Golgi to plasma membrane transport
      pfam16692
      Location:344 → 566
      Folliculin_C; Folliculin C-terminal domain

    9. XM_028835485.1 → XP_028691318.1  folliculin isoform X1

      UniProtKB/TrEMBL
      F6XBF6, G7NJ12, H9ERY6
      Conserved Domains (2) summary
      pfam11704
      Location:106 → 265
      Folliculin; Vesicle coat protein involved in Golgi to plasma membrane transport
      pfam16692
      Location:344 → 566
      Folliculin_C; Folliculin C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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