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    MYCN MYCN proto-oncogene, bHLH transcription factor [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 698699, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MYCNprovided by VGNC
    Official Full Name
    MYCN proto-oncogene, bHLH transcription factorprovided by VGNC
    Primary source
    VGNC:VGNC:106187
    See related
    Ensembl:ENSMMUG00000052363
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MYCN in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 13 NC_041766.1 (92961946..92968585, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 13 NC_027905.1 (15903117..15909685)

    Chromosome 13 - NC_041766.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA40 Neighboring gene uncharacterized LOC106992845 Neighboring gene small nucleolar RNA U13 Neighboring gene 60S acidic ribosomal protein P1-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    N-myc proto-oncogene protein
    Names
    v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
    v-myc myelocytomatosis viral related oncogene, neuroblastoma derived

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041766.1 Reference Mmul_10 Primary Assembly

      Range
      92961946..92968585 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001091369.4 → XP_001091369.3  N-myc proto-oncogene protein isoform X1

      UniProtKB/TrEMBL
      A0A5F8AH13
      Related
      ENSMMUP00000076691.1, ENSMMUT00000087245.1
      Conserved Domains (2) summary
      cd00083
      Location:470 → 529
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam01056
      Location:101 → 463
      Myc_N; Myc amino-terminal region

    2. XM_015111747.2 → XP_014967233.2  N-myc proto-oncogene protein isoform X2

      Conserved Domains (2) summary
      cd11456
      Location:378 → 464
      bHLHzip_N-Myc_like; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in N-Myc and similar proteins
      pfam01056
      Location:10 → 372
      Myc_N; Myc amino-terminal region
    Nucleotide Protein
    Heading Accession and Version

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    Research Materials