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    ARHGAP23 Rho GTPase activating protein 23 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 693996, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ARHGAP23provided by VGNC
    Official Full Name
    Rho GTPase activating protein 23provided by VGNC
    Primary source
    VGNC:VGNC:99116
    See related
    Ensembl:ENSMMUG00000020020
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ARHGAP23 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (49471848..49567357)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (44100841..44197444)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 179 Neighboring gene suppressor of cytokine signaling 7 Neighboring gene uncharacterized LOC114673143 Neighboring gene SRC kinase signaling inhibitor 1 Neighboring gene elongin BC and polycomb repressive complex 2 associated protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rho GTPase-activating protein 23

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      49471848..49567357
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015119489.2 → XP_014974975.2  rho GTPase-activating protein 23 isoform X2

      UniProtKB/TrEMBL
      A0A1D5R487, F7GJ03
      Related
      ENSMMUP00000026324.4, ENSMMUT00000028137.4
      Conserved Domains (4) summary
      PHA03247
      Location:167 → 570
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:23 → 133
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd04395
      Location:884 → 1079
      RhoGAP_ARHGAP21; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the cell-cell junction ...
      cd01253
      Location:672 → 792
      PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain

    2. XM_015119488.2 → XP_014974974.2  rho GTPase-activating protein 23 isoform X1

      UniProtKB/TrEMBL
      A0A1D5R3H8, A0A1D5R487
      Related
      ENSMMUP00000054864.2, ENSMMUT00000074669.2
      Conserved Domains (4) summary
      PHA03247
      Location:185 → 588
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:41 → 151
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd04395
      Location:902 → 1097
      RhoGAP_ARHGAP21; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the cell-cell junction ...
      cd01253
      Location:690 → 810
      PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain

    3. XM_028836424.1 → XP_028692257.1  rho GTPase-activating protein 23 isoform X3

      UniProtKB/TrEMBL
      A0A1D5R487
      Conserved Domains (4) summary
      PHA03247
      Location:185 → 588
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:41 → 151
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd04395
      Location:819 → 1014
      RhoGAP_ARHGAP21; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the cell-cell junction ...
      cl17171
      Location:590 → 727
      PH-like; Pleckstrin homology-like domain

    4. XM_028836426.1 → XP_028692259.1  rho GTPase-activating protein 23 isoform X4

      UniProtKB/TrEMBL
      H9EQV4
      Conserved Domains (4) summary
      PHA03247
      Location:91 → 494
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:4 → 57
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd04395
      Location:808 → 1003
      RhoGAP_ARHGAP21; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the cell-cell junction ...
      cd01253
      Location:596 → 716
      PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain

    5. XM_015119490.2 → XP_014974976.1  rho GTPase-activating protein 23 isoform X4

      UniProtKB/TrEMBL
      H9EQV4
      Related
      ENSMMUP00000074709.1, ENSMMUT00000089659.1
      Conserved Domains (4) summary
      PHA03247
      Location:91 → 494
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:4 → 57
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd04395
      Location:808 → 1003
      RhoGAP_ARHGAP21; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the cell-cell junction ...
      cd01253
      Location:596 → 716
      PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain

    6. XM_028836427.1 → XP_028692260.1  rho GTPase-activating protein 23 isoform X5

      UniProtKB/TrEMBL
      H9EQV4
      Conserved Domains (3) summary
      PHA03247
      Location:34 → 437
      PHA03247; large tegument protein UL36; Provisional
      cd04395
      Location:751 → 946
      RhoGAP_ARHGAP21; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the cell-cell junction ...
      cd01253
      Location:539 → 659
      PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain

    7. XM_015119491.2 → XP_014974977.1  rho GTPase-activating protein 23 isoform X6

      UniProtKB/TrEMBL
      A0A5F8AGJ3, H9EQV4
      Related
      ENSMMUP00000076984.1, ENSMMUT00000090613.1
      Conserved Domains (3) summary
      cd04395
      Location:696 → 891
      RhoGAP_ARHGAP21; RhoGAP_ARHGAP21: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the ...
      cd01253
      Location:484 → 604
      PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain
      pfam00169
      Location:483 → 602
      PH; PH domain
    Nucleotide Protein
    Heading Accession and Version

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