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    AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 693652, updated on 17-Aug-2024

    Summary

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    Official Symbol
    AGAP1provided by VGNC
    Official Full Name
    ArfGAP with GTPase domain, ankyrin repeat and PH domain 1provided by VGNC
    Primary source
    VGNC:VGNC:84206
    See related
    Ensembl:ENSMMUG00000009346
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See AGAP1 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 12 NC_041765.1 (122909049..123554112)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 12 NC_027904.1 (118073773..118838251)

    Chromosome 12 - NC_041765.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114671447 Neighboring gene uncharacterized LOC114671448 Neighboring gene uncharacterized LOC106992778 Neighboring gene prohibitin pseudogene Neighboring gene gastrulation brain homeobox 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1
    NP_001248562.1
    XP_014966714.2
    XP_014966715.2
    XP_014966716.2
    XP_014966717.2
    XP_014966719.2
    XP_014966720.1
    XP_014966721.1
    XP_014966722.1
    XP_014966723.1
    XP_028686208.1
    XP_028686209.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261633.1 → NP_001248562.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

      See identical proteins and their annotated locations for NP_001248562.1

      Status: PROVISIONAL

      Source sequence(s)
      JU322158
      UniProtKB/TrEMBL
      F7HJG4, H9EU55, H9FPN4
      Related
      ENSMMUP00000012244.3, ENSMMUT00000013063.4
      Conserved Domains (5) summary
      cd04103
      Location:72 → 229
      Centaurin_gamma; Centaurin gamma (CENTG) GTPase
      cd00204
      Location:735 → 822
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01250
      Location:344 → 592
      PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
      sd00045
      Location:768 → 799
      ANK; ANK repeat [structural motif]
      pfam01412
      Location:611 → 725
      ArfGap; Putative GTPase activating protein for Arf

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041765.1 Reference Mmul_10 Primary Assembly

      Range
      122909049..123554112
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015111237.2 → XP_014966723.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform X11

      UniProtKB/TrEMBL
      F7HJG4, H9FPN4, I0FFX0
      Conserved Domains (5) summary
      cd04103
      Location:72 → 229
      Centaurin_gamma; Centaurin gamma (CENTG) GTPase
      cd00204
      Location:682 → 769
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01250
      Location:344 → 539
      PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
      sd00045
      Location:715 → 746
      ANK; ANK repeat [structural motif]
      pfam01412
      Location:558 → 672
      ArfGap; Putative GTPase activating protein for Arf

    2. XM_015111234.2 → XP_014966720.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform X8

      UniProtKB/TrEMBL
      F7HJG4, H9FPN4
      Conserved Domains (5) summary
      cd04103
      Location:72 → 233
      Centaurin_gamma; Centaurin gamma (CENTG) GTPase
      cd00204
      Location:764 → 851
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01250
      Location:348 → 621
      PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
      sd00045
      Location:797 → 828
      ANK; ANK repeat [structural motif]
      pfam01412
      Location:640 → 754
      ArfGap; Putative GTPase activating protein for Arf

    3. XM_015111236.2 → XP_014966722.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform X10

      UniProtKB/TrEMBL
      F7HJG4, H9FPN4, H9FPN7
      Conserved Domains (5) summary
      cd04103
      Location:72 → 233
      Centaurin_gamma; Centaurin gamma (CENTG) GTPase
      cd00204
      Location:686 → 773
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01250
      Location:348 → 543
      PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
      sd00045
      Location:719 → 750
      ANK; ANK repeat [structural motif]
      pfam01412
      Location:562 → 676
      ArfGap; Putative GTPase activating protein for Arf

    4. XM_015111235.2 → XP_014966721.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform X9

      UniProtKB/TrEMBL
      F7HJG4, H9FPN4
      Conserved Domains (5) summary
      cd04103
      Location:72 → 229
      Centaurin_gamma; Centaurin gamma (CENTG) GTPase
      cd00204
      Location:760 → 847
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd01250
      Location:344 → 617
      PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
      sd00045
      Location:793 → 824
      ANK; ANK repeat [structural motif]
      pfam01412
      Location:636 → 750
      ArfGap; Putative GTPase activating protein for Arf

    5. XM_015111229.2 → XP_014966715.2  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A5F8A7Q8, A0A5F8AAR2
      Related
      ENSMMUP00000074010.1, ENSMMUT00000103573.1
      Conserved Domains (6) summary
      cd04103
      Location:337 → 494
      Centaurin_gamma; Centaurin gamma (CENTG) GTPase
      PHA03307
      Location:5 → 208
      PHA03307; transcriptional regulator ICP4; Provisional
      cd01250
      Location:609 → 882
      PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
      sd00045
      Location:1058 → 1089
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:1026 → 1116
      Ank_2; Ankyrin repeats (3 copies)
      cd08853
      Location:899 → 1007
      ArfGap_AGAP2; ArfGAP with GTPase domain, ANK repeat and PH domain 2

    6. XM_015111228.2 → XP_014966714.2  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A5F8A7Q8, A0A5F8ARV3
      Related
      ENSMMUP00000080685.1, ENSMMUT00000093715.1
      Conserved Domains (6) summary
      cd04103
      Location:337 → 498
      Centaurin_gamma; Centaurin gamma (CENTG) GTPase
      PHA03307
      Location:5 → 208
      PHA03307; transcriptional regulator ICP4; Provisional
      cd01250
      Location:613 → 886
      PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
      sd00045
      Location:1062 → 1093
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:1030 → 1120
      Ank_2; Ankyrin repeats (3 copies)
      cd08853
      Location:903 → 1011
      ArfGap_AGAP2; ArfGAP with GTPase domain, ANK repeat and PH domain 2

    7. XM_015111230.2 → XP_014966716.2  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A5F8A7Q8
      Related
      ENSMMUP00000073412.1, ENSMMUT00000103755.1
      Conserved Domains (6) summary
      cd04103
      Location:337 → 498
      Centaurin_gamma; Centaurin gamma (CENTG) GTPase
      PHA03307
      Location:5 → 208
      PHA03307; transcriptional regulator ICP4; Provisional
      cd01250
      Location:613 → 861
      PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
      sd00045
      Location:1037 → 1068
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:1005 → 1095
      Ank_2; Ankyrin repeats (3 copies)
      cd08853
      Location:878 → 986
      ArfGap_AGAP2; ArfGAP with GTPase domain, ANK repeat and PH domain 2

    8. XM_015111231.2 → XP_014966717.2  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform X4

      UniProtKB/TrEMBL
      F7HJG6
      Related
      ENSMMUP00000012243.4, ENSMMUT00000013062.4
      Conserved Domains (6) summary
      cd04103
      Location:337 → 498
      Centaurin_gamma; Centaurin gamma (CENTG) GTPase
      PHA03307
      Location:5 → 208
      PHA03307; transcriptional regulator ICP4; Provisional
      cd01250
      Location:613 → 833
      PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
      sd00045
      Location:1009 → 1040
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:977 → 1067
      Ank_2; Ankyrin repeats (3 copies)
      cd08853
      Location:850 → 958
      ArfGap_AGAP2; ArfGAP with GTPase domain, ANK repeat and PH domain 2

    9. XM_028830376.1 → XP_028686209.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform X7

      Conserved Domains (6) summary
      cd04103
      Location:337 → 498
      Centaurin_gamma; Centaurin gamma (CENTG) GTPase
      PHA03307
      Location:5 → 208
      PHA03307; transcriptional regulator ICP4; Provisional
      cd01250
      Location:613 → 754
      PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
      sd00045
      Location:930 → 961
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:898 → 988
      Ank_2; Ankyrin repeats (3 copies)
      cd08853
      Location:771 → 879
      ArfGap_AGAP2; ArfGAP with GTPase domain, ANK repeat and PH domain 2

    10. XM_028830375.1 → XP_028686208.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform X6

      Conserved Domains (6) summary
      cd04103
      Location:337 → 494
      Centaurin_gamma; Centaurin gamma (CENTG) GTPase
      PHA03307
      Location:5 → 208
      PHA03307; transcriptional regulator ICP4; Provisional
      cd01250
      Location:609 → 804
      PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
      sd00045
      Location:980 → 1011
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:948 → 1038
      Ank_2; Ankyrin repeats (3 copies)
      cd08853
      Location:821 → 929
      ArfGap_AGAP2; ArfGAP with GTPase domain, ANK repeat and PH domain 2

    11. XM_015111233.2 → XP_014966719.2  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform X5

      Conserved Domains (6) summary
      cd04103
      Location:337 → 498
      Centaurin_gamma; Centaurin gamma (CENTG) GTPase
      PHA03307
      Location:5 → 208
      PHA03307; transcriptional regulator ICP4; Provisional
      cd01250
      Location:613 → 808
      PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
      sd00045
      Location:984 → 1015
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:952 → 1042
      Ank_2; Ankyrin repeats (3 copies)
      cd08853
      Location:825 → 933
      ArfGap_AGAP2; ArfGAP with GTPase domain, ANK repeat and PH domain 2
    Nucleotide Protein
    Heading Accession and Version

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