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    ALOX5 arachidonate 5-lipoxygenase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 707926, updated on 17-Aug-2024

    Summary

    Official Symbol
    ALOX5provided by VGNC
    Official Full Name
    arachidonate 5-lipoxygenaseprovided by VGNC
    Primary source
    VGNC:VGNC:69798
    See related
    Ensembl:ENSMMUG00000013434
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
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    Genomic context

    See ALOX5 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 9 NC_041762.1 (46585862..46646535)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 9 NC_027901.1 (40947964..41008660)

    Chromosome 9 - NC_041762.1Genomic Context describing neighboring genes Neighboring gene olfactory receptor 6C75-like Neighboring gene olfactory receptor, family 13, subfamily A, member 1 Neighboring gene uncharacterized LOC114669943 Neighboring gene membrane associated ring-CH-type finger 8 Neighboring gene zinc finger AN1-type containing 4

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables arachidonate 5-lipoxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in linoleic acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in lipid oxidation IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in nuclear envelope IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    arachidonate 5-lipoxygenase
    XP_001102354.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041762.1 Reference Mmul_10 Primary Assembly

      Range
      46585862..46646535
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001102354.4XP_001102354.1  arachidonate 5-lipoxygenase

      See identical proteins and their annotated locations for XP_001102354.1

      UniProtKB/TrEMBL
      A0A1D5QJX2, G7N1W6
      Related
      ENSMMUP00000048345.1, ENSMMUT00000069966.2
      Conserved Domains (2) summary
      cd01753
      Location:2115
      PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
      pfam00305
      Location:227665
      Lipoxygenase; Lipoxygenase