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    MAMU-DOB major histocompatibility complex, class II, DO beta [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 717702, updated on 5-Mar-2024

    Summary

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    Gene symbol
    MAMU-DOB
    Gene description
    major histocompatibility complex, class II, DO beta
    See related
    Ensembl:ENSMMUG00000011293
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MAMU-DOB in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (136716221..136720516)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (33621672..33625962, complement)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106997907 Neighboring gene proteasome 20S subunit beta 8 Neighboring gene transporter 2, ATP binding cassette subfamily B member Neighboring gene major histocompatibility complex, class II, DQ beta 1 Neighboring gene major histocompatibility complex, class II, DQ alpha 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables MHC class II protein complex binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in antigen processing and presentation of exogenous peptide antigen via MHC class II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immunoglobulin production involved in immunoglobulin-mediated immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptide antigen assembly with MHC class II protein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of T cell activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of MHC class II protein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    major histocompatibility complex, class II, DO beta

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001194682.3 → NP_001181611.2  major histocompatibility complex, class II, DO beta precursor

      Status: PROVISIONAL

      Source sequence(s)
      QNVO02000341
      UniProtKB/TrEMBL
      F6WA04, G7MRN4
      Related
      ENSMMUP00000014796.3, ENSMMUT00000015792.4
      Conserved Domains (3) summary
      pfam00969
      Location:39 → 113
      MHC_II_beta; Class II histocompatibility antigen, beta domain
      cd00096
      Location:122 → 130
      Ig; Ig strand A [structural motif]
      cl11960
      Location:120 → 215
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      136716221..136720516
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials