PPA2 inorganic pyrophosphatase 2 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: PPA2provided by VGNC
Official Full Name: inorganic pyrophosphatase 2provided by VGNC
Primary source: VGNC:VGNC:96721
See related: Ensembl:ENSMMUG00000017004
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	5	NC_041758.1 (103851242..103962915, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	5	NC_027897.1 (104859968..105005007)

Chromosome 5 - NC_041758.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

SHGC-67401 (e-PCR)
- UniSTS:3082

SHGC-67245 (e-PCR)
- UniSTS:43787

D4S3026 (e-PCR)
- UniSTS:48111

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables inorganic diphosphate phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables magnesium ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in phosphate-containing compound metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: inorganic pyrophosphatase 2, mitochondrial

Names: pyrophosphatase (inorganic) 2

XP_014994412.1

EC 3.6.1.1

XP_028704489.1

EC 3.6.1.1

XP_028704490.1

EC 3.6.1.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041758.1 Reference Mmul_10 Primary Assembly

Range

103851242..103962915 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015138926.2 → XP_014994412.1 inorganic pyrophosphatase 2, mitochondrial isoform X2

UniProtKB/TrEMBL

F6PN98, H9F5C5

Related

ENSMMUP00000022377.4, ENSMMUT00000023906.4

Conserved Domains (1) summary

cl00217
Location:4 → 286

pyrophosphatase; Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers.
XM_028848657.1 → XP_028704490.1 inorganic pyrophosphatase 2, mitochondrial isoform X3

UniProtKB/TrEMBL

A0A5F8A9L4

Conserved Domains (1) summary

cl00217
Location:27 → 222

pyrophosphatase; Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers.
XM_028848656.1 → XP_028704489.1 inorganic pyrophosphatase 2, mitochondrial isoform X1

UniProtKB/TrEMBL

A0A5F8A9L4

Conserved Domains (1) summary

cl00217
Location:70 → 302

pyrophosphatase; Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers.