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    CD226 CD226 molecule [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 703878, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CD226provided by VGNC
    Official Full Name
    CD226 moleculeprovided by VGNC
    Primary source
    VGNC:VGNC:101435
    See related
    Ensembl:ENSMMUG00000052693
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    PTA1
    Orthologs
    human mouse all
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    Genomic context

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    See CD226 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 18 NC_041771.1 (9973984..10073063)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 18 NC_027910.1 (59920262..60022250, complement)

    Chromosome 18 - NC_041771.1Genomic Context describing neighboring genes Neighboring gene rotatin Neighboring gene uncharacterized LOC114673742 Neighboring gene microRNA mir-7173 Neighboring gene uncharacterized LOC114673685 Neighboring gene uncharacterized LOC114673802 Neighboring gene docking protein 6 Neighboring gene uncharacterized LOC114673822

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation of cDNAs encoding gibbon and monkey platelet and T cell activation antigen 1 (PTA1). Tian F, et al. DNA Seq, 1999. PMID 10647817
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in cytokine production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of Fc receptor mediated stimulatory signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of T cell receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of immunoglobulin mediated immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of mast cell activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of natural killer cell cytokine production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of type II interferon production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    CD226 antigen
    Names
    platelet and T cell activation antigen 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001042643.1 → NP_001036108.1  CD226 antigen precursor

      See identical proteins and their annotated locations for NP_001036108.1

      Status: PROVISIONAL

      Source sequence(s)
      AF030432
      UniProtKB/Swiss-Prot
      O18906
      UniProtKB/TrEMBL
      G7NKW1
      Related
      ENSMMUP00000076685.1, ENSMMUT00000106648.1
      Conserved Domains (2) summary
      smart00410
      Location:136 → 240
      IG_like; Immunoglobulin like
      cl11960
      Location:31 → 127
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041771.1 Reference Mmul_10 Primary Assembly

      Range
      9973984..10073063
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028837741.1 → XP_028693574.1  CD226 antigen isoform X2

      Conserved Domains (1) summary
      cl11960
      Location:28 → 110
      Ig; Immunoglobulin domain

    2. XM_015122176.2 → XP_014977662.1  CD226 antigen isoform X1

      UniProtKB/TrEMBL
      A0A5F8AI57, G7NKW1
      Conserved Domains (2) summary
      smart00410
      Location:136 → 240
      IG_like; Immunoglobulin like
      cl11960
      Location:31 → 127
      Ig; Immunoglobulin domain

    3. XM_028837740.1 → XP_028693573.1  CD226 antigen isoform X2

      Conserved Domains (1) summary
      cl11960
      Location:28 → 110
      Ig; Immunoglobulin domain

    4. XM_015122175.2 → XP_014977661.1  CD226 antigen isoform X1

      UniProtKB/TrEMBL
      A0A5F8AI57, G7NKW1
      Conserved Domains (2) summary
      smart00410
      Location:136 → 240
      IG_like; Immunoglobulin like
      cl11960
      Location:31 → 127
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O18906.1 GenPept UniProtKB/Swiss-Prot:O18906

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials