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    MBL2 mannose binding lectin 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 702652, updated on 5-Mar-2024

    Summary

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    Gene symbol
    MBL2
    Gene description
    mannose binding lectin 2
    See related
    Ensembl:ENSMMUG00000046929
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    MBP-C
    Orthologs
    human mouse all
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    Genomic context

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    See MBL2 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 9 NC_041762.1 (85179875..85185072)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 9 NC_027901.1 (80044106..80049568)

    Chromosome 9 - NC_041762.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107000197 Neighboring gene uncharacterized LOC107000198 Neighboring gene uncharacterized LOC114669991 Neighboring gene uncharacterized LOC107000207

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of two mannose-binding protein cDNAs from rhesus monkey (Macaca mulatta): structure and evolutionary implications. Mogues T, et al. Glycobiology, 1996 Jul. PMID 8877375
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in positive regulation of phagocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in surfactant homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in multivesicular body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in rough endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mannose-binding protein C
    Names
    mannose-binding lectin (protein C) 2, soluble (opsonic defect)
    mannose-binding lectin 2, soluble

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105535.3 → NP_001099005.3  mannose-binding protein C precursor

      Status: VALIDATED

      Source sequence(s)
      QNVO02000497
      UniProtKB/TrEMBL
      G7N2G0
      Conserved Domains (2) summary
      cd03591
      Location:136 → 246
      CLECT_collectin_like; C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1)
      pfam01391
      Location:41 → 99
      Collagen; Collagen triple helix repeat (20 copies)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041762.1 Reference Mmul_10 Primary Assembly

      Range
      85179875..85185072
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015147559.2 → XP_015003045.2  mannose-binding protein C isoform X2

      UniProtKB/TrEMBL
      G7N2G0
      Conserved Domains (2) summary
      cd03591
      Location:136 → 246
      CLECT_collectin_like; C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1)
      pfam01391
      Location:41 → 99
      Collagen; Collagen triple helix repeat (20 copies)

    2. XM_015147558.2 → XP_015003044.2  mannose-binding protein C isoform X1

      UniProtKB/TrEMBL
      A0A1D5R122, G7N2G0
      Related
      ENSMMUP00000054006.2, ENSMMUT00000068519.2
      Conserved Domains (2) summary
      cd03591
      Location:143 → 253
      CLECT_collectin_like; C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1)
      pfam01391
      Location:48 → 106
      Collagen; Collagen triple helix repeat (20 copies)
    Nucleotide Protein
    Heading Accession and Version

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