TRIM22 tripartite motif containing 22 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: TRIM22provided by VGNC
Official Full Name: tripartite motif containing 22provided by VGNC
Primary source: VGNC:VGNC:79031
Locus tag: EGK_06566
See related: Ensembl:ENSMMUG00000000338
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human all
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Genomic context

Location:: chromosome: 14

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	14	NC_041767.1 (62515425..62535168, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	14	NC_027906.1 (61427091..61446817, complement)

Chromosome 14 - NC_041767.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Constitutive TRIM22 Expression in the Respiratory Tract Confers a Pre-Existing Defence Against Influenza A Virus Infection.
Title: Constitutive TRIM22 Expression in the Respiratory Tract Confers a Pre-Existing Defence Against Influenza A Virus Infection.
Data show that RNA interference abolished IFN-gamma-induced TRIM22 expression, indicating an IRF-1-dependent expression of TRIM22.
Title: A 5' extended IFN-stimulating response element is crucial for IFN-gamma-induced tripartite motif 22 expression via interaction with IFN regulatory factor-1.
Study shows that human and rhesus TRIM22 localise to different subcellular compartments and that this difference can be assigned to the positively selected B30.2 domain.
Title: Different subcellular localisations of TRIM22 suggest species-specific function.

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General gene information

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Markers

ECD03124 (e-PCR)
- UniSTS:284211

REN99243 (e-PCR)
- UniSTS:424040

REN99250 (e-PCR)
- UniSTS:424047

REN99251 (e-PCR)
- UniSTS:424048

REN99252 (e-PCR)
- UniSTS:424049

REN99260 (e-PCR)
- UniSTS:424057

REN99261 (e-PCR)
- UniSTS:424058

REN99262 (e-PCR)
- UniSTS:424059

REN99266 (e-PCR)
- UniSTS:424063

REN99276 (e-PCR)
- UniSTS:424073

REN99282 (e-PCR)
- UniSTS:424079

ECD06572 (e-PCR)
- UniSTS:287632

REN99283 (e-PCR)
- UniSTS:424080

REN99285 (e-PCR)
- UniSTS:424082

REN99286 (e-PCR)
- UniSTS:424083

ECD24318 (e-PCR)
- UniSTS:305302

REN99293 (e-PCR)
- UniSTS:424090

ECD00903 (e-PCR)
- UniSTS:282012

REN99297 (e-PCR)
- UniSTS:424094

REN99300 (e-PCR)
- UniSTS:424097

REN99301 (e-PCR)
- UniSTS:424098

REN99305 (e-PCR)
- UniSTS:424102

REN99306 (e-PCR)
- UniSTS:424103

D11S4036 (e-PCR)
- UniSTS:75947

ECD01210 (e-PCR)
- UniSTS:282317

stSG611162 (e-PCR)
- UniSTS:449264

stSG611163 (e-PCR)
- UniSTS:449265

stSG611164 (e-PCR)
- UniSTS:449266

stSG611168 (e-PCR)
- UniSTS:449269

stSG611169 (e-PCR)
- UniSTS:449270

stSG611170 (e-PCR)
- UniSTS:449271

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: E3 ubiquitin-protein ligase TRIM22

NP_001106830.1

EC 2.3.2.27

XP_014970521.1

EC 2.3.2.27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001113359.1 → NP_001106830.1 E3 ubiquitin-protein ligase TRIM22

See identical proteins and their annotated locations for NP_001106830.1

Status: PROVISIONAL

Source sequence(s)

EU124697

UniProtKB/TrEMBL

A0A8J8XB53, B0F4M8, F6YNA9, G7NE30

Related

ENSMMUP00000068533.1, ENSMMUT00000087777.1

Conserved Domains (4) summary

smart00336
Location:92 → 133

BBOX; B-Box-type zinc finger

pfam15035
Location:129 → 205

Rootletin; Ciliary rootlet component, centrosome cohesion

cl02614
Location:299 → 496

SPRY; SPRY domain

cl17238
Location:15 → 59

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041767.1 Reference Mmul_10 Primary Assembly

Range

62515425..62535168 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015115035.2 → XP_014970521.1 E3 ubiquitin-protein ligase TRIM22 isoform X1

UniProtKB/TrEMBL

A0A8J8XB53, B0F4M8, F6YNA9, G7NE30

Related

ENSMMUP00000000460.2, ENSMMUT00000000496.4

Conserved Domains (4) summary

smart00336
Location:92 → 133

BBOX; B-Box-type zinc finger

pfam15035
Location:129 → 205

Rootletin; Ciliary rootlet component, centrosome cohesion

cl02614
Location:299 → 496

SPRY; SPRY domain

cl17238
Location:15 → 59

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...