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    SPTLC3 serine palmitoyltransferase long chain base subunit 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 693775, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SPTLC3provided by VGNC
    Official Full Name
    serine palmitoyltransferase long chain base subunit 3provided by VGNC
    Primary source
    VGNC:VGNC:77929
    Locus tag
    EGK_02675
    See related
    Ensembl:ENSMMUG00000000089
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SPTLC3 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (53383692..53556808, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (46024777..46195420)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene taspase 1 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene uncharacterized LOC107000452 Neighboring gene isthmin 1 Neighboring gene uncharacterized LOC107000475 Neighboring gene uncharacterized LOC107000492

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables serine C-palmitoyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ceramide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sphingosine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of serine palmitoyltransferase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine palmitoyltransferase 3
    XP_015004972.1
    XP_028684014.1
    XP_028684015.1
    XP_028684016.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      53383692..53556808 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028828183.1 → XP_028684016.1  serine palmitoyltransferase 3 isoform X4

      UniProtKB/TrEMBL
      A0A5K1UIL0, F7HAI1
      Related
      ENSMMUP00000000121.4, ENSMMUT00000000132.4
      Conserved Domains (1) summary
      PLN02483
      Location:57 → 514
      PLN02483; serine palmitoyltransferase

    2. XM_015149486.2 → XP_015004972.1  serine palmitoyltransferase 3 isoform X2

      UniProtKB/TrEMBL
      F7HAI1
      Conserved Domains (2) summary
      PLN02483
      Location:57 → 519
      PLN02483; serine palmitoyltransferase
      COG0156
      Location:109 → 523
      BioF; 7-keto-8-aminopelargonate synthetase or related enzyme [Coenzyme transport and metabolism]

    3. XM_028828181.1 → XP_028684014.1  serine palmitoyltransferase 3 isoform X1

      UniProtKB/TrEMBL
      A0A5F8AB94, A0A8J8YHF2, F7HAI1, F7HAI3, G7N2Z5
      Related
      ENSMMUP00000075208.1, ENSMMUT00000099521.1
      Conserved Domains (1) summary
      cl18945
      Location:57 → 549
      AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...

    4. XM_028828182.1 → XP_028684015.1  serine palmitoyltransferase 3 isoform X3

      UniProtKB/TrEMBL
      F7HAI1
      Conserved Domains (1) summary
      PLN02483
      Location:57 → 514
      PLN02483; serine palmitoyltransferase
    Nucleotide Protein
    Heading Accession and Version

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