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    C1S complement C1s [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 714589, updated on 17-Aug-2024

    Summary

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    Official Symbol
    C1Sprovided by VGNC
    Official Full Name
    complement C1sprovided by VGNC
    Primary source
    VGNC:VGNC:70297
    See related
    Ensembl:ENSMMUG00000012786
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See C1S in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (7248992..7259592)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (7393034..7403622)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene lysophosphatidylcholine acyltransferase 3 Neighboring gene uncharacterized LOC100430245 Neighboring gene complement C1r Neighboring gene complement C1s subcomponent-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in complement activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    complement C1s subcomponent
    XP_015006437.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      7248992..7259592
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015150951.2 → XP_015006437.2  complement C1s subcomponent

      UniProtKB/TrEMBL
      F7EI47, H9FZ52
      Related
      ENSMMUP00000076188.1, ENSMMUT00000090107.1
      Conserved Domains (5) summary
      cd00033
      Location:359 → 422
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
      cd00041
      Location:18 → 129
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00190
      Location:438 → 678
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
      pfam00431
      Location:175 → 287
      CUB; CUB domain
      pfam14670
      Location:143 → 171
      FXa_inhibition; Coagulation Factor Xa inhibitory site
    Nucleotide Protein
    Heading Accession and Version

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