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    athp-1 PHD-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 176517, updated on 9-Dec-2024

    Summary

    Official Symbol
    athp-1
    Official Full Name
    PHD-type domain-containing protein
    Primary source
    WormBase:WBGene00008081
    Locus tag
    CELE_C44B9.4
    See related
    AllianceGenome:WB:WBGene00008081
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be part of Sin3-type complex. Predicted to be active in nucleus. Orthologous to human PHF12 (PHD finger protein 12). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See athp-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    12
    Sequence:
    Chromosome: III; NC_003281.10 (10882360..10893672)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Vps54_N domain-containing protein Neighboring gene Lgl_C domain-containing protein Neighboring gene CUB domain-containing protein Neighboring gene F-box domain-containing protein Neighboring gene DNA endonuclease activator Ctp1 C-terminal domain-containing protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transcription corepressor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of Sin3-type complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    PHD-type domain-containing protein
    NP_499397.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      10882360..10893672
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066996.7NP_499397.2  PHD-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499397.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18605
      Conserved Domains (3) summary
      smart00240
      Location:10191076
      FHA; Forkhead associated domain
      cd15534
      Location:220266
      PHD2_PHF12_Rco1; PHD finger 2 found in PHD finger protein 12 (PHF12), yeast Rco1, and similar proteins
      cd15567
      Location:62103
      PHD4_NSD; PHD finger 4 found in nuclear receptor-binding SET domain-containing (NSD) proteins