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    cpf-1 Cleavage stimulation factor 50 kDa subunit [ Caenorhabditis elegans ]

    Gene ID: 174378, updated on 9-Dec-2024

    Summary

    Official Symbol
    cpf-1
    Official Full Name
    Cleavage stimulation factor 50 kDa subunit
    Primary source
    WormBase:WBGene00000773
    Locus tag
    CELE_F28C6.3
    See related
    AllianceGenome:WB:WBGene00000773
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in mRNA 3'-end processing. Predicted to be located in nucleus. Predicted to be part of mRNA cleavage stimulating factor complex. Orthologous to human CSTF1 (cleavage stimulation factor subunit 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See cpf-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003280.10 (8600449..8602440, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Transcription factor aptf-4 Neighboring gene Transcription factor AP-2 C-terminal domain-containing protein Neighboring gene GPI ethanolamine phosphate transferase 2 Neighboring gene Amelotin Neighboring gene ncRNA Neighboring gene Large ribosomal subunit protein uL24 Neighboring gene Suppressor of forked domain-containing protein

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in mRNA 3'-end processing IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of mRNA cleavage stimulating factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of mRNA cleavage stimulating factor complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Cleavage stimulation factor 50 kDa subunit
    NP_495822.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      8600449..8602440 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063421.7NP_495822.1  Cleavage stimulation factor 50 kDa subunit [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495822.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19864
      Conserved Domains (3) summary
      cd00200
      Location:101421
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:114168
      7WD40; WD40 repeat [structural motif]
      pfam16699
      Location:360
      CSTF1_dimer; Cleavage stimulation factor subunit 1, dimerization domain