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    ctsa-2 Carboxypeptidase [ Caenorhabditis elegans ]

    Gene ID: 180915, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ctsa-2
    Official Full Name
    Carboxypeptidase
    Primary source
    WormBase:WBGene00019617
    Locus tag
    CELE_K10C2.1
    See related
    AllianceGenome:WB:WBGene00019617
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable serine-type carboxypeptidase activity. Predicted to be involved in proteolysis. Located in membrane raft. Is expressed in intestine. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ctsa-2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    21
    Sequence:
    Chromosome: X; NC_003284.9 (6421036..6430610, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Transmembrane protein Neighboring gene Ubiquitin-like domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Gustatory receptor Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Age-related behaviors have distinct transcriptional profiles in Caenorhabditis elegans. Golden TR, et al. Aging Cell, 2008 Dec. PMID 18778409, Free PMC Article
    2. An analysis of the Caenorhabditis elegans lipid raft proteome using geLC-MS/MS. Rao W, et al. J Proteomics, 2011 Feb 1. PMID 21070894
    3. Improved Biocompatibility of Amino-Functionalized Graphene Oxide in Caenorhabditis elegans. Rive C, et al. Small, 2019 Nov. PMID 31576668
    4. Lysosome activity is modulated by multiple longevity pathways and is important for lifespan extension in C. elegans. Sun Y, et al. Elife, 2020 Jun 2. PMID 32482227, Free PMC Article
    5. Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences. Zhang X, et al. PLoS Genet, 2021 Jun. PMID 34166401, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables carboxypeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type carboxypeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables serine-type carboxypeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane raft HDA PubMed 

    General protein information

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    Preferred Names
    Carboxypeptidase
    NP_509079.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      6421036..6430610 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076678.6 → NP_509079.2  Carboxypeptidase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509079.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q94269
      Conserved Domains (3) summary
      pfam00450
      Location:581 → 1047
      Peptidase_S10; Serine carboxypeptidase
      pfam06752
      Location:2193 → 2301
      E_Pc_C; Enhancer of Polycomb C-terminus
      pfam11914
      Location:2195 → 2291
      DUF3432; Domain of unknown function (DUF3432)
    Nucleotide Protein
    Heading Accession and Version

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