U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ech-3 Enoyl-CoA hydratase [ Caenorhabditis elegans ]

    Gene ID: 179180, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ech-3
    Official Full Name
    Enoyl-CoA hydratase
    Primary source
    WormBase:WBGene00001152
    Locus tag
    CELE_F43H9.1
    See related
    AllianceGenome:WB:WBGene00001152
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in IRE1-mediated unfolded protein response. Is expressed in intestine. [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ech-3 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    3
    Sequence:
    Chromosome: V; NC_003283.11 (8022217..8023317)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene BSD domain-containing protein Neighboring gene Serine palmitoyltransferase 2 Neighboring gene Poly(A) RNA polymerase mitochondrial-like central palm domain-containing protein Neighboring gene ncRNA Neighboring gene Glycine N-acyltransferase-like protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Exposure to 6-PPD quinone enhances lipid accumulation through activating metabolic sensors of SBP-1 and MDT-15 in Caenorhabditis elegans. Wang Y, et al. Environ Pollut, 2023 Sep 15. PMID 37307863
    2. Serotonin regulates C. elegans fat and feeding through independent molecular mechanisms. Srinivasan S, et al. Cell Metab, 2008 Jun. PMID 18522834, Free PMC Article
    3. Systems-level transcriptional regulation of Caenorhabditis elegans metabolism. Nanda S, et al. Mol Syst Biol, 2023 May 9. PMID 36942755, Free PMC Article
    4. Fatty acid desaturation and the regulation of adiposity in Caenorhabditis elegans. Brock TJ, et al. Genetics, 2007 Jun. PMID 17435249, Free PMC Article
    5. A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49. Van Gilst MR, et al. Proc Natl Acad Sci U S A, 2005 Sep 20. PMID 16157872, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in IRE1-mediated unfolded protein response HEP PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    Enoyl-CoA hydratase
    NP_001309646.1
    • Confirmed by transcript evidence
    NP_505066.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      8022217..8023317
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072665.7 → NP_505066.1  Enoyl-CoA hydratase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505066.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20376
      Conserved Domains (1) summary
      cl23717
      Location:7 → 247
      crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...

    2. NM_001322576.3 → NP_001309646.1  Enoyl-CoA hydratase [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A131MCK1
      Conserved Domains (1) summary
      cl23717
      Location:4 → 198
      crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools