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    mrp-6 Multidrug resistance-associated protein lethal(2)03659 [ Caenorhabditis elegans ]

    Gene ID: 180691, updated on 9-Dec-2024

    Summary

    Official Symbol
    mrp-6
    Official Full Name
    Multidrug resistance-associated protein lethal(2)03659
    Primary source
    WormBase:WBGene00003412
    Locus tag
    CELE_F20B6.3
    See related
    AllianceGenome:WB:WBGene00003412
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in membrane. Is expressed in hypodermis; intestine; and nervous system. Orthologous to human ABCC4 (ATP binding cassette subfamily C member 4 (PEL blood group)). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See mrp-6 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    18
    Sequence:
    Chromosome: X; NC_003284.9 (4177989..4186756, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene MD-2-related lipid-recognition domain-containing protein Neighboring gene ncRNA Neighboring gene V-type proton ATPase subunit B 1 Neighboring gene Envelope glycoprotein UL132

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ABC-type transporter activity  
    enables ATP binding  
    enables ATP hydrolysis activity  
    enables ATPase-coupled transmembrane transporter activity  
    Process Evidence Code Pubs
    involved_in transmembrane transport  
    involved_in transmembrane transport  
    Component Evidence Code Pubs
    is_active_in membrane  
    located_in membrane  

    General protein information

    Preferred Names
    Multidrug resistance-associated protein lethal(2)03659
    NP_001362008.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      4177989..4186756 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001375011.2NP_001362008.1  Multidrug resistance-associated protein lethal(2)03659 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19625
      Conserved Domains (1) summary
      TIGR00957
      Location:1261389
      MRP_assoc_pro; multi drug resistance-associated protein (MRP)
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