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    ugt-13 glucuronosyltransferase [ Caenorhabditis elegans ]

    Gene ID: 186766, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ugt-13
    Official Full Name
    glucuronosyltransferase
    Primary source
    WormBase:WBGene00019232
    Locus tag
    CELE_H23N18.1
    See related
    AllianceGenome:WB:WBGene00019232
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Orthologous to human UGT8 (UDP glycosyltransferase 8); UGT3A1 (UDP glycosyltransferase family 3 member A1); and UGT3A2 (UDP glycosyltransferase family 3 member A2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ugt-13 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    8
    Sequence:
    Chromosome: V; NC_003283.11 (4908884..4911399)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene glucuronosyltransferase Neighboring gene glucuronosyltransferase Neighboring gene Venom protein Neighboring gene Transmembrane protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. Hasegawa K, et al. PLoS One, 2010 Feb 17. PMID 20174640, Free PMC Article
    2. Adaptive and specialised transcriptional responses to xenobiotic stress in Caenorhabditis elegans are regulated by nuclear hormone receptors. Jones LM, et al. PLoS One, 2013. PMID 23922869, Free PMC Article
    3. UDP-glycosyltransferase family in Haemonchus contortus: Phylogenetic analysis, constitutive expression, sex-differences and resistance-related differences. Matoušková P, et al. Int J Parasitol Drugs Drug Resist, 2018 Dec. PMID 30293057, Free PMC Article
    4. Differential expression of genes in C. elegans reveals transcriptional responses to indirect-acting xenobiotic compounds and insensitivity to 2,3,7,8-tetrachlorodibenzodioxin. Karengera A, et al. Ecotoxicol Environ Saf, 2022 Mar 15. PMID 35219257
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables UDP-glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables UDP-glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glucuronosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    glucuronosyltransferase
    NP_504317.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      4908884..4911399
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_071916.8 → NP_504317.2  glucuronosyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504317.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9TXZ6
      Conserved Domains (2) summary
      PHA03392
      Location:1 → 509
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      pfam00201
      Location:29 → 514
      UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase
    Nucleotide Protein
    Heading Accession and Version

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