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    • Showing Current items.

    dyf-7 Protein dyf-7 [ Caenorhabditis elegans ]

    Gene ID: 181183, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dyf-7
    Official Full Name
    Protein dyf-7
    Primary source
    WormBase:WBGene00001123
    Locus tag
    CELE_C43C3.3
    See related
    AllianceGenome:WB:WBGene00001123
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in amphid sensory organ dendrite retrograde extension and neuron projection extension. Located in dendrite membrane. Is expressed in excretory cell; nervous system; and seam cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See dyf-7 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    11
    Sequence:
    Chromosome: X; NC_003284.9 (9698659..9701732)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Neuropeptide receptor 18 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Suppressor protein SRP40 Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A dyf-7 haplotype causes sensory neuron defects and is associated with macrocyclic lactone resistance worldwide in the nematode parasite Haemonchus contortus. Urdaneta-Marquez L, et al. Int J Parasitol, 2014 Dec. PMID 25224687
    2. Loss of the Extracellular Matrix Protein DIG-1 Causes Glial Fragmentation, Dendrite Breakage, and Dendrite Extension Defects. Chong MK, et al. J Dev Biol, 2021 Oct 7. PMID 34698211, Free PMC Article
    3. Morphogenesis of neurons and glia within an epithelium. Low IIC, et al. Development, 2019 Feb 20. PMID 30683663, Free PMC Article
    4. DEX-1 and DYF-7 establish sensory dendrite length by anchoring dendritic tips during cell migration. Heiman MG, et al. Cell, 2009 Apr 17. PMID 19344940, Free PMC Article
    5. Epithelial Shaping by Diverse Apical Extracellular Matrices Requires the Nidogen Domain Protein DEX-1 in Caenorhabditis elegans. Cohen JD, et al. Genetics, 2019 Jan. PMID 30409789, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in amphid sensory organ dendrite retrograde extension IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in amphid sensory organ dendrite retrograde extension IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in anatomical structure morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in neuron projection extension IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in dendrite IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in dendrite membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Protein dyf-7
    NP_001379066.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      9698659..9701732
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001392826.1 → NP_001379066.1  Protein dyf-7 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q09276
      Conserved Domains (1) summary
      cl27758
      Location:36 → 288
      Zona_pellucida; Zona pellucida-like domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q09276.2

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