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    sek-4 mitogen-activated protein kinase kinase [ Caenorhabditis elegans ]

    Gene ID: 180811, updated on 9-Dec-2024

    Summary

    Official Symbol
    sek-4
    Official Full Name
    mitogen-activated protein kinase kinase
    Primary source
    WormBase:WBGene00018035
    Locus tag
    CELE_F35C8.2
    See related
    AllianceGenome:WB:WBGene00018035
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable MAP kinase kinase activity. Predicted to be involved in stress-activated MAPK cascade. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See sek-4 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    8
    Sequence:
    Chromosome: X; NC_003284.9 (5375059..5377042)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Dual specificity mitogen-activated protein kinase kinase jkk-1 Neighboring gene Uncharacterized protein Neighboring gene pseudo Neighboring gene mitogen-activated protein kinase kinase Neighboring gene ncRNA

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables MAP kinase kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in stress-activated MAPK cascade IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    mitogen-activated protein kinase kinase
    NP_508915.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      5375059..5377042
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076514.8NP_508915.3  mitogen-activated protein kinase kinase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508915.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q58AU8
      Conserved Domains (1) summary
      cl21453
      Location:57324
      PKc_like; Protein Kinases, catalytic domain