D1069.3 COP9 signalosome complex subunit 3;Hyccin [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: D1069.3
Official Full Name: COP9 signalosome complex subunit 3;Hyccin
Primary source: WormBase:WBGene00017037
Locus tag: CELE_D1069.3
See related: AllianceGenome:WB:WBGene00017037
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be involved in phosphatidylinositol phosphate biosynthetic process and protein localization to plasma membrane. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 5. Orthologous to human HYCC1 (hyccin PI4KA lipid kinase complex subunit 1) and HYCC2 (hyccin PI4KA lipid kinase complex subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See D1069.3 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 9

Sequence:: Chromosome: II; NC_003280.10 (341716..347891, complement)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

D1069.3 (e-PCR)
- UniSTS:320260

D1069.4 (e-PCR)
- UniSTS:313968

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in phosphatidylinositol phosphate biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein localization to plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: COP9 signalosome complex subunit 3;Hyccin

NP_001022050.1

Confirmed by transcript evidence

NP_001368514.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

341716..347891 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001026879.2 → NP_001022050.1 Hyccin [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001022050.1

Status: REVIEWED

UniProtKB/TrEMBL

Q6A586

Conserved Domains (1) summary

pfam09790
Location:50 → 356

Hyccin; Hyccin
NM_001381313.1 → NP_001368514.1 COP9 signalosome complex subunit 3 [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A0K3ARJ1

Conserved Domains (1) summary

pfam09790
Location:3 → 40

Hyccin