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    blos-4 Biogenesis of lysosome-related organelles complex 1 subunit 4 [ Caenorhabditis elegans ]

    Gene ID: 188869, updated on 9-Dec-2024

    Summary

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    Official Symbol
    blos-4
    Official Full Name
    Biogenesis of lysosome-related organelles complex 1 subunit 4
    Primary source
    WormBase:WBGene00020783
    Locus tag
    CELE_T24H7.4
    See related
    AllianceGenome:WB:WBGene00020783
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in endosomal transport. Predicted to be part of BLOC-1 complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See blos-4 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003280.10 (6245249..6246323)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene GyrI-like small molecule binding domain-containing protein Neighboring gene Phospholipid-transporting ATPase Neighboring gene Small vasohibin-binding protein Neighboring gene GSKIP domain-containing protein Neighboring gene Hypoxia up-regulated protein 1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. C. elegans BLOC-1 functions in trafficking to lysosome-related gut granules. Hermann GJ, et al. PLoS One, 2012. PMID 22916203, Free PMC Article
    2. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in endosomal transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of BLOC-1 complex TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Biogenesis of lysosome-related organelles complex 1 subunit 4
    NP_495247.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      6245249..6246323
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_062846.4 → NP_495247.1  Biogenesis of lysosome-related organelles complex 1 subunit 4 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495247.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q22756
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q22756.1

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