U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    picc-1 PAC-1 interacting and coiled-coil domain-containing protein 1 [ Caenorhabditis elegans ]

    Gene ID: 3564810, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    picc-1
    Official Full Name
    PAC-1 interacting and coiled-coil domain-containing protein 1
    Primary source
    WormBase:WBGene00017931
    Locus tag
    CELE_F29G9.2
    See related
    AllianceGenome:WB:WBGene00017931
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in adherens junction. Orthologous to several human genes including CCDC85C (coiled-coil domain containing 85C). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See picc-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    7
    Sequence:
    Chromosome: V; NC_003283.11 (6018994..6026338)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene AP complex subunit sigma Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Retinol dehydrogenase 14 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. An instructive role for C. elegans E-cadherin in translating cell contact cues into cortical polarity. Klompstra D, et al. Nat Cell Biol, 2015 Jun. PMID 25938815, Free PMC Article
    2. Regulation of Cdc42 and its effectors in epithelial morphogenesis. Pichaud F, et al. J Cell Sci, 2019 May 21. PMID 31113848
    3. Protein interaction mapping in C. elegans using proteins involved in vulval development. Walhout AJ, et al. Science, 2000 Jan 7. PMID 10615043
    4. A combined binary interaction and phenotypic map of C. elegans cell polarity proteins. Koorman T, et al. Nat Cell Biol, 2016 Mar. PMID 26780296, Free PMC Article
    5. C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Reboul J, et al. Nat Genet, 2003 May. PMID 12679813

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in adherens junction IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in anchoring junction IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    PAC-1 interacting and coiled-coil domain-containing protein 1
    NP_001370415.1
    • Confirmed by transcript evidence
    NP_504560.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      6018994..6026338
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072159.7 → NP_504560.1  PAC-1 interacting and coiled-coil domain-containing protein 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504560.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      H2KYP0, Q8IA85
      Conserved Domains (1) summary
      pfam10226
      Location:113 → 239
      DUF2216; Uncharacterized conserved proteins (DUF2216)

    2. NM_001383314.2 → NP_001370415.1  PAC-1 interacting and coiled-coil domain-containing protein 1 [Caenorhabditis elegans]

      Status: REVIEWED

      Conserved Domains (1) summary
      pfam10226
      Location:103 → 262
      CCDC85; CCDC85 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    H2KYP0.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools