npp-23 WD_REPEATS_REGION domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: npp-23
Official Full Name: WD_REPEATS_REGION domain-containing protein
Primary source: WormBase:WBGene00007493
Locus tag: CELE_C09G9.2
See related: AllianceGenome:WB:WBGene00007493
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Located in kinetochore. Part of nuclear pore. Orthologous to human NUP43 (nucleoporin 43). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See npp-23 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 8

Sequence:: Chromosome: IV; NC_003282.8 (8868036..8869679, complement)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C09G9.3 (e-PCR)
- UniSTS:321923

C09G9.2 (e-PCR)
- UniSTS:313522

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Component	Evidence Code	Pubs
located_in kinetochore	IMP Inferred from Mutant Phenotype more info	PubMed
part_of nuclear pore	IMP Inferred from Mutant Phenotype more info	PubMed
part_of nuclear pore outer ring	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: WD_REPEATS_REGION domain-containing protein

NP_001129845.1

Confirmed by transcript evidence

NP_501537.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

8868036..8869679 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_069136.4 → NP_501537.2 WD_REPEATS_REGION domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_501537.2

Status: REVIEWED

UniProtKB/TrEMBL

Q17872

Conserved Domains (3) summary

COG2319
Location:20 → 357

WD40; WD40 repeat [General function prediction only]

sd00039
Location:133 → 166

7WD40; WD40 repeat [structural motif]

cl02567
Location:96 → 329

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
NM_001136373.4 → NP_001129845.1 WD_REPEATS_REGION domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001129845.1

Status: REVIEWED

UniProtKB/TrEMBL

B3GWB1

Conserved Domains (3) summary

COG2319
Location:46 → 276

WD40; WD40 repeat [General function prediction only]

sd00039
Location:41 → 74

7WD40; WD40 repeat [structural motif]

cl02567
Location:4 → 237

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...