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    F54C9.9 Protein KRI1 homolog [ Caenorhabditis elegans ]

    Gene ID: 174374, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F54C9.9
    Official Full Name
    Protein KRI1 homolog
    Primary source
    WormBase:WBGene00010044
    Locus tag
    CELE_F54C9.9
    See related
    AllianceGenome:WB:WBGene00010044
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be part of 90S preribosome. Predicted to be active in nucleolus. Orthologous to human KRI1 (KRI1 homolog). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F54C9.9 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    11
    Sequence:
    Chromosome: II; NC_003280.10 (8578049..8581513)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Pumilio domain-containing protein 5 Neighboring gene ADP-ribosylation factor-like protein 1 Neighboring gene GDP/GTP exchange factor Sec2 N-terminal domain-containing protein Neighboring gene Transcription factor aptf-4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. FACT Sets a Barrier for Cell Fate Reprogramming in Caenorhabditis elegans and Human Cells. Kolundzic E, et al. Dev Cell, 2018 Sep 10. PMID 30078731, Free PMC Article
    2. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
    3. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
    4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of 90S preribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Protein KRI1 homolog
    NP_495815.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      8578049..8581513
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063414.5 → NP_495815.1  Protein KRI1 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495815.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20760
      Conserved Domains (2) summary
      pfam05178
      Location:329 → 420
      Kri1; KRI1-like family
      pfam12936
      Location:507 → 595
      Kri1_C; KRI1-like family C-terminal
    Nucleotide Protein
    Heading Accession and Version

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