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    nduc-2 NADH dehydrogenase [ubiquinone] 1 subunit C2 [ Caenorhabditis elegans ]

    Gene ID: 175397, updated on 9-Dec-2024

    Summary

    Official Symbol
    nduc-2
    Official Full Name
    NADH dehydrogenase [ubiquinone] 1 subunit C2
    Primary source
    WormBase:WBGene00022169
    Locus tag
    CELE_Y71H2AM.4
    See related
    AllianceGenome:WB:WBGene00022169
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex I. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency. Orthologous to human NDUFC2 (NADH:ubiquinone oxidoreductase subunit C2) and NDUFC2-KCTD14 (NDUFC2-KCTD14 readthrough). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See nduc-2 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    2
    Sequence:
    Chromosome: III; NC_003281.10 (2786852..2788028)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene DNA/pantothenate metabolism flavoprotein C-terminal domain-containing protein;Myotubularin phosphatase domain-containing protein Neighboring gene Serine/threonine-protein phosphatase 2A activator Neighboring gene Cytochrome oxidase c subunit VIb Neighboring gene C-CAP/cofactor C-like domain-containing protein Neighboring gene Potassium channel domain-containing protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, NADH to ubiquinone IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of respiratory chain complex I IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    NADH dehydrogenase [ubiquinone] 1 subunit C2
    NP_001380068.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      2786852..2788028
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001393299.1NP_001380068.1  NADH dehydrogenase [ubiquinone] 1 subunit C2 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9BL33
      Conserved Domains (1) summary
      pfam06374
      Location:31132
      NDUF_C2; NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2)