U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Y41D4A.6 Amidase domain-containing protein;Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial [ Caenorhabditis elegans ]

    Gene ID: 176982, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Y41D4A.6
    Official Full Name
    Amidase domain-containing protein;Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial
    Primary source
    WormBase:WBGene00021508
    Locus tag
    CELE_Y41D4A.6
    See related
    AllianceGenome:WB:WBGene00021508
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity. Predicted to be involved in glutaminyl-tRNAGln biosynthesis via transamidation and mitochondrial translation. Predicted to be part of glutamyl-tRNA(Gln) amidotransferase complex. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 40. Orthologous to human QRSL1 (glutaminyl-tRNA amidotransferase subunit QRSL1). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Y41D4A.6 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    5
    Sequence:
    Chromosome: IV; NC_003282.8 (1740447..1745503, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Ascaris suum EPICuticlin protein related Neighboring gene CC domain-containing protein Neighboring gene Protein-tyrosine-phosphatase Neighboring gene Transmembrane 9 superfamily member Neighboring gene BUB1 N-terminal domain-containing protein Neighboring gene F-box associated domain-containing protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in glutaminyl-tRNAGln biosynthesis via transamidation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in glutaminyl-tRNAGln biosynthesis via transamidation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitochondrial translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of glutamyl-tRNA(Gln) amidotransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of glutamyl-tRNA(Gln) amidotransferase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Amidase domain-containing protein;Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial
    NP_001294547.1
    • Confirmed by transcript evidence
    NP_001294548.1
    • Confirmed by transcript evidence
    NP_001368303.1
    • Confirmed by transcript evidence
    NP_001368304.1
    • Confirmed by transcript evidence
    NP_001368305.1
    • Confirmed by transcript evidence
    NP_500129.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      1740447..1745503 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067728.7 → NP_500129.1  Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500129.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95Y25
      Conserved Domains (1) summary
      PRK00012
      Location:20 → 446
      gatA; aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed

    2. NM_001307618.3 → NP_001294547.1  Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294547.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PC78
      Conserved Domains (1) summary
      PRK00012
      Location:20 → 448
      gatA; aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed

    3. NM_001380058.1 → NP_001368303.1  Amidase domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PF27
      Conserved Domains (1) summary
      cl18951
      Location:2 → 154
      Amidase

    4. NM_001307619.1 → NP_001294548.1  Amidase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294548.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PMM1
      Conserved Domains (1) summary
      cl18951
      Location:2 → 156
      Amidase

    5. NM_001380059.1 → NP_001368304.1  Amidase domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PBV0
      Conserved Domains (1) summary
      cl18951
      Location:1 → 133
      Amidase

    6. NM_001380060.1 → NP_001368305.1  Amidase domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PRY3
      Conserved Domains (1) summary
      cl18951
      Location:1 → 135
      Amidase
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools