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    Y48G8AL.13 TLC domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 171699, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y48G8AL.13
    Official Full Name
    TLC domain-containing protein
    Primary source
    WormBase:WBGene00021691
    Locus tag
    CELE_Y48G8AL.13
    See related
    AllianceGenome:WB:WBGene00021691
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in several processes, including membrane assembly; phospholipid homeostasis; and regulation of membrane lipid distribution. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human TLCD2 (TLC domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y48G8AL.13 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003279.8 (1223961..1226812, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene HECT domain-containing protein Neighboring gene FIP (Fungus-Induced Protein) Related;Fungus-induced protein 1 Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene nucleoside-diphosphate kinase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in membrane assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in phospholipid homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in plasma membrane organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of membrane lipid distribution IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    TLC domain-containing protein
    NP_001293436.2
    • Confirmed by transcript evidence
    NP_490836.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      1223961..1226812 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058435.9 → NP_490836.1  TLC domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_490836.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9BL09
      Conserved Domains (1) summary
      smart00724
      Location:35 → 242
      TLC; TRAM, LAG1 and CLN8 homology domains

    2. NM_001306507.4 → NP_001293436.2  TLC domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      W6RR25
      Conserved Domains (1) summary
      cl02759
      Location:1 → 156
      TRAM_LAG1_CLN8; TLC domain
    Nucleotide Protein
    Heading Accession and Version

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