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    twk-17 Potassium channel domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 181024, updated on 9-Dec-2024

    Summary

    Official Symbol
    twk-17
    Official Full Name
    Potassium channel domain-containing protein
    Primary source
    WormBase:WBGene00006671
    Locus tag
    CELE_C44E12.3
    See related
    AllianceGenome:WB:WBGene00006671
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in neurons. Orthologous to human KCNK17 (potassium two pore domain channel subfamily K member 17) and KCNK5 (potassium two pore domain channel subfamily K member 5). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See twk-17 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    14
    Sequence:
    Chromosome: X; NC_003284.9 (7599806..7608082, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene A disintegrin and metalloproteinase with thrombospondin motifs adt-2;Peptidase M12B domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Peptidase M20 dimerization domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables outward rectifier potassium channel activity  
    enables potassium channel activity  
    enables potassium ion leak channel activity  
    Component Evidence Code Pubs
    located_in membrane  
    is_active_in plasma membrane  

    General protein information

    Preferred Names
    Potassium channel domain-containing protein
    NP_001024462.1
    • Confirmed by transcript evidence
    NP_001024463.1
    • Confirmed by transcript evidence
    NP_001024464.1
    • Confirmed by transcript evidence
    NP_001024465.1
    • Confirmed by transcript evidence
    NP_001024466.1
    • Confirmed by transcript evidence
    NP_001024467.1
    • Confirmed by transcript evidence
    NP_001360693.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      7599806..7608082 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001029294.4 → NP_001024465.1  Potassium channel domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024465.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O76794
      Conserved Domains (1) summary
      pfam07885
      Location:242 → 299
      Ion_trans_2; Ion channel
    2. NM_001373367.3 → NP_001360693.1  Potassium channel domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4V0IK48
      Conserved Domains (1) summary
      pfam07885
      Location:178 → 234
      Ion_trans_2; Ion channel
    3. NM_001029296.8 → NP_001024467.1  Potassium channel domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024467.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EFI2
      Conserved Domains (1) summary
      pfam07885
      Location:178 → 235
      Ion_trans_2; Ion channel
    4. NM_001029292.3 → NP_001024463.1  Potassium channel domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024463.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O76788
      Conserved Domains (1) summary
      pfam07885
      Location:178 → 235
      Ion_trans_2; Ion channel
    5. NM_001029293.3 → NP_001024464.1  Potassium channel domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024464.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O76791
      Conserved Domains (1) summary
      pfam07885
      Location:242 → 299
      Ion_trans_2; Ion channel
    6. NM_001029291.3 → NP_001024462.1  Potassium channel domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024462.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KZB5
      Conserved Domains (1) summary
      pfam07885
      Location:185 → 242
      Ion_trans_2; Ion channel
    7. NM_001029295.5 → NP_001024466.1  Potassium channel domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024466.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O76792
      Conserved Domains (1) summary
      pfam07885
      Location:242 → 299
      Ion_trans_2; Ion channel
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