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    Ramacl RNA guanine-7 methyltransferase activating subunit like [ Mus musculus (house mouse) ]

    Gene ID: 100038538, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ramaclprovided by MGI
    Official Full Name
    RNA guanine-7 methyltransferase activating subunit likeprovided by MGI
    Primary source
    MGI:MGI:3642136
    See related
    Ensembl:ENSMUSG00000074826 AllianceGenome:MGI:3642136
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm10767
    Summary
    Predicted to enable RNA binding activity and enzyme activator activity. Predicted to be located in nucleus. Predicted to be part of mRNA cap methyltransferase RNMT:RAMAC complex and mRNA capping enzyme complex. Orthologous to human RAMAC (RNA guanine-7 methyltransferase activating subunit) and RAMACL (RNA guanine-7 methyltransferase activating subunit like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 3.3), CNS E14 (RPKM 2.9) and 26 other tissues See more
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    Genomic context

    See Ramacl in Genome Data Viewer
    Location:
    13 B3; 13 34.54 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (67053479..67057230)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (66905415..66909166)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_34888 Neighboring gene high mobility group box 2 pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:67006259-67006368 Neighboring gene ubiquinol-cytochrome c reductase binding protein Neighboring gene mitochondrial transcription termination factor 3 Neighboring gene STARR-positive B cell enhancer ABC_E10799 Neighboring gene STARR-seq mESC enhancer starr_34889 Neighboring gene phosphatidylserine synthase 1 Neighboring gene RIKEN cDNA 4933433G19 gene Neighboring gene STARR-seq mESC enhancer starr_34892 Neighboring gene zinc finger protein 712 Neighboring gene STARR-positive B cell enhancer ABC_E3085

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables enzyme activator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables molecular function activator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    part_of mRNA cap methyltransferase RNMT:RAMAC complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of mRNA capping enzyme complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of mRNA capping enzyme complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    RNA guanine-N7 methyltransferase activating subunit-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001177750.1NP_001171221.1  RNA guanine-N7 methyltransferase activating subunit-like

      See identical proteins and their annotated locations for NP_001171221.1

      Status: VALIDATED

      Source sequence(s)
      AC124433
      Consensus CDS
      CCDS56889.1
      UniProtKB/TrEMBL
      Q3TQP0
      Related
      ENSMUSP00000133648.2, ENSMUST00000099412.3
      Conserved Domains (1) summary
      pfam15320
      Location:1084
      RAM; mRNA cap methylation, RNMT-activating mini protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      67053479..67057230
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)