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    Atl2 atlastin GTPase 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298757, updated on 9-Dec-2024

    Summary

    Official Symbol
    Atl2provided by RGD
    Official Full Name
    atlastin GTPase 2provided by RGD
    Primary source
    RGD:1305125
    See related
    EnsemblRapid:ENSRNOG00000006523 AllianceGenome:RGD:1305125
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Arl6ip2
    Summary
    Predicted to enable GTP binding activity; GTPase activity; and identical protein binding activity. Predicted to be involved in Golgi organization; endoplasmic reticulum tubular network membrane organization; and protein homooligomerization. Predicted to be located in endoplasmic reticulum tubular network membrane. Orthologous to human ATL2 (atlastin GTPase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 456.2), Liver (RPKM 345.0) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Atl2 in Genome Data Viewer
    Location:
    6q12
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (20891220..20932644)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (15139071..15180421)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (2568975..2610432)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein L-like Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC134479323 Neighboring gene uncharacterized LOC134479324 Neighboring gene uncharacterized LOC108351158 Neighboring gene uncharacterized LOC102554703 Neighboring gene uncharacterized LOC134479104

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in Golgi organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in endoplasmic reticulum organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in endoplasmic reticulum organization ISO
    Inferred from Sequence Orthology
    more info
     
    NOT involved_in endoplasmic reticulum to Golgi vesicle-mediated transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in endoplasmic reticulum tubular network membrane organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein homooligomerization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein homooligomerization ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum tubular network membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    atlastin-2
    Names
    ADP-ribosylation factor-like 6 interacting protein 2
    NP_001094141.1
    XP_063117669.1
    XP_063117670.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001100671.1NP_001094141.1  atlastin-2

      Status: VALIDATED

      Source sequence(s)
      BC092650, CB580536, CO395790, EV762626
      UniProtKB/TrEMBL
      F1LQ09
      Related
      ENSRNOP00000106218.1, ENSRNOT00000172058.1
      Conserved Domains (1) summary
      pfam02263
      Location:70341
      GBP; Guanylate-binding protein, N-terminal domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      20891220..20932644
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063261599.1XP_063117669.1  atlastin-2 isoform X1

      UniProtKB/TrEMBL
      F1LQ09
    2. XM_063261600.1XP_063117670.1  atlastin-2 isoform X2

      UniProtKB/TrEMBL
      F1LQ09
      Related
      ENSRNOP00000071967.2, ENSRNOT00000077543.3