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    Map2 microtubule-associated protein 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25595, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Map2provided by RGD
    Official Full Name
    microtubule-associated protein 2provided by RGD
    Primary source
    RGD:3044
    See related
    EnsemblRapid:ENSRNOG00000011841 AllianceGenome:RGD:3044
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    MAP2R; Mtap2
    Summary
    Enables actin binding activity; microtubule binding activity; and protein kinase binding activity. Involved in several processes, including negative regulation of cellular component organization; positive regulation of vesicle transport along microtubule; and response to progesterone. Located in several cellular components, including axon; cytoskeleton; and dendrite. Part of protein-containing complex. Is active in glutamatergic synapse and postsynapse. Used to study Alzheimer's disease and cerebral infarction. Biomarker of arteriovenous malformation; asphyxia neonatorum; brain ischemia; sciatic neuropathy; and temporal lobe epilepsy. Orthologous to human MAP2 (microtubule associated protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 797.4) and Adrenal (RPKM 83.9) See more
    Orthologs
    human mouse all
    NEW
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    Genomic context

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    See Map2 in Genome Data Viewer
    Location:
    9q32
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (75173038..75431606)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (67723422..67981886)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (73204753..73462965)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene crystallin, gamma F Neighboring gene splicing regulatory glutamic acid and lysine rich protein 1, pseudogene 1 Neighboring gene unc-80 homolog, NALCN channel complex subunit Neighboring gene KAT8 regulatory NSL complex subunit 1-like Neighboring gene ribulose-5-phosphate-3-epimerase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A mouse model of term chorioamnionitis: unraveling causes of adverse neurological outcomes. Burd I, et al. Reprod Sci, 2011 Sep. PMID 21421895, Free PMC Article
    2. [Effects of low-dose X-ray on morphology of neuron and expression of microtubule associated protein-2 in hippocampus of young rats]. Zhang W, et al. Zhonghua Yi Xue Za Zhi, 2012 Feb 7. PMID 22490839
    3. Functional improvement and neuroplastic effects of anodal transcranial direct current stimulation (tDCS) delivered 1 day vs. 1 week after cerebral ischemia in rats. Yoon KJ, et al. Brain Res, 2012 May 3. PMID 22444278
    4. BACE1 elevation is associated with aberrant limbic axonal sprouting in epileptic CD1 mice. Yan XX, et al. Exp Neurol, 2012 May. PMID 22265658, Free PMC Article
    5. An experimental rat model of sporadic Alzheimer's disease and rescue of cognitive impairment with a neurotrophic peptide. Bolognin S, et al. Acta Neuropathol, 2012 Jan. PMID 22083255, Free PMC Article

    See all (134) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. NEP140 promotes myelin regeneration via upregulation of GAP43 and MAP2 expression after focal cerebral ischemia in rats.
      Title: NEP1‑40 promotes myelin regeneration via upregulation of GAP‑43 and MAP‑2 expression after focal cerebral ischemia in rats.
    2. Human Milk Oligosaccharide 2'-Fucosyllactose Induces Neuroprotection from Intracerebral Hemorrhage Stroke.
      Title: Human Milk Oligosaccharide 2'-Fucosyllactose Induces Neuroprotection from Intracerebral Hemorrhage Stroke.
    3. Protein Expression Profile on Differentiation of Bone Marrow Mesenchymal Stem Cells into Retinal Ganglion-Like Cells.
      Title: Protein Expression Profile on Differentiation of Bone Marrow Mesenchymal Stem Cells into Retinal Ganglion-Like Cells.
    4. Microtubule-associated protein 2 mediates induction of long-term potentiation in hippocampal neurons.
      Title: Microtubule-associated protein 2 mediates induction of long-term potentiation in hippocampal neurons.
    5. Effects of combined electroacupuncture and exercise training on motor function and microtubule-associated protein 2 expression in the middle and late stages of cerebral infarction in rats.
      Title: Effects of combined electroacupuncture and exercise training on motor function and microtubule-associated protein 2 expression in the middle and late stages of cerebral infarction in rats.
    6. inhibition of cell death in post-conditioned ischemic rats was found to be regulated by some neuroprotective molecules as well as MAP-2
      Title: Age-related difference in protective effect of early post-conditioning on ischemic brain injury: possible involvement of MAP-2/Synaptophysin role.
    7. investigates the expression of autophagy-related protein Beclin-1 and microtubule-associated protein 2 light chain 3 (LC3) in periodontal ligament cells in orthodontic tooth pressure areas
      Title: [Expression of autophagy-related protein Beclin-1 and microtubule-associated protein 2 light chain 3 in periodontal ligament cells in orthodontic tooth pressure areas].
    8. selective axonal cargo trafficking requires the MAP2-defined pre-axonal filtering zone and the ability of cargos to switch between distinct kinesin motor activities
      Title: MAP2 Defines a Pre-axonal Filtering Zone to Regulate KIF1- versus KIF5-Dependent Cargo Transport in Sensory Neurons.
    9. dephosphorylation of MAP2D at Thr256 and Thr259, phosphorylation of vimentin at Ser38 and Ser72, and the resulting enhanced binding of MAP2D to vimentin might contribute to the progesterone synthetic response required for ovulation.
      Title: Dephosphorylation of MAP2D enhances its binding to vimentin in preovulatory ovarian granulosa cells.
    10. analysis of MAP2c phosphorylation and regulatory protein 14-3-3zeta-binding sites, which reveals key differences between MAP2c and its homolog Tau
      Title: Quantitative mapping of microtubule-associated protein 2c (MAP2c) phosphorylation and regulatory protein 14-3-3ζ-binding sites reveals key differences between MAP2c and its homolog Tau.
    Submit: New GeneRIF Correction See all GeneRIFs (58)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables actin binding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables dystroglycan binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables dystroglycan binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables microtubule binding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables microtubule binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within axonogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in central nervous system neuron development IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in central nervous system neuron development ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within dendrite development ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in dendrite morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in dendrite morphogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within establishment of cell polarity ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within microtubule bundle formation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in microtubule cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of axon extension IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of axon extension ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of microtubule depolymerization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of microtubule polymerization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in neuron projection development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in neuron projection development ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of anterograde dense core granule transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of anterograde synaptic vesicle transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of organelle transport along microtubule IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of protein localization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of protein localization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in response to estradiol IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to progesterone IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in CA3 pyramidal cell dendrite ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in actin cytoskeleton IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in apical dendrite ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in apical distal dendrite IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in axon hillock IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in axon hillock ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in axon initial segment IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in axon initial segment ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in basal dendrite IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cell body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cell body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in dendrite IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in dendrite ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in dendrite cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in dendritic branch IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in dendritic filopodium IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in dendritic growth cone IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in dendritic shaft IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in dendritic shaft ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in distal dendrite IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    NOT located_in main axon IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in microtubule cytoskeleton IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in neuron projection IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in neuron projection ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in neuronal cell body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nuclear periphery ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in postsynapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in primary dendrite IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of protein-containing complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in proximal dendrite IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in proximal neuron projection IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in proximal neuron projection ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in ruffle membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    microtubule-associated protein 2
    Names
    microtubule-associated protein 2C

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001431749.1 → NP_001418678.1  microtubule-associated protein 2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A0A8I6GHK9

    2. NM_001431750.1 → NP_001418679.1  microtubule-associated protein 2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A0A8I6GHK9

    3. NM_001431751.1 → NP_001418680.1  microtubule-associated protein 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/Swiss-Prot
      P15146

    4. NM_001431752.1 → NP_001418681.1  microtubule-associated protein 2 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      Q64715

    5. NM_001431753.1 → NP_001418682.1  microtubule-associated protein 2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A6KFC4, Q64715

    6. NM_001431754.1 → NP_001418683.1  microtubule-associated protein 2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A0A0U1RS04, A0A9K3Y814, E9PTL3, Q78DZ1

    7. NM_001431755.1 → NP_001418684.1  microtubule-associated protein 2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A0A0U1RS04, A0A9K3Y814, E9PTL3, Q78DZ1

    8. NM_001431756.1 → NP_001418685.1  microtubule-associated protein 2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A0A0U1RS04, A0A9K3Y814, E9PTL3, Q78DZ1

    9. NM_001431757.1 → NP_001418686.1  microtubule-associated protein 2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A0A0U1RS04, A0A9K3Y814, E9PTL3, Q78DZ1

    10. NM_001431762.1 → NP_001418691.1  microtubule-associated protein 2 isoform 6

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A0A0U1RS04

    11. NM_013066.2 → NP_037198.2  microtubule-associated protein 2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A6KFC4, Q64715

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      75173038..75431606
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063266724.1 → XP_063122794.1  microtubule-associated protein 2 isoform X11

      UniProtKB/Swiss-Prot
      P15146

    2. XM_063266731.1 → XP_063122801.1  microtubule-associated protein 2 isoform X16

    3. XM_063266715.1 → XP_063122785.1  microtubule-associated protein 2 isoform X8

      UniProtKB/Swiss-Prot
      P15146
      UniProtKB/TrEMBL
      F1MAQ5

    4. XM_063266720.1 → XP_063122790.1  microtubule-associated protein 2 isoform X9

      UniProtKB/Swiss-Prot
      P15146

    5. XM_063266734.1 → XP_063122804.1  microtubule-associated protein 2 isoform X20

    6. XM_063266718.1 → XP_063122788.1  microtubule-associated protein 2 isoform X10

      UniProtKB/Swiss-Prot
      P15146

    7. XM_017596293.3 → XP_017451782.1  microtubule-associated protein 2 isoform X1

      UniProtKB/Swiss-Prot
      P15146
      UniProtKB/TrEMBL
      F1LNK0
      Conserved Domains (3) summary
      PTZ00449
      Location:1498 → 1772
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam08377
      Location:460 → 1593
      MAP2_projctn; MAP2/Tau projection domain
      pfam00418
      Location:1776 → 1806
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    8. XM_063266713.1 → XP_063122783.1  microtubule-associated protein 2 isoform X6

    9. XM_063266707.1 → XP_063122777.1  microtubule-associated protein 2 isoform X3

      UniProtKB/Swiss-Prot
      P15146

    10. XM_063266717.1 → XP_063122787.1  microtubule-associated protein 2 isoform X9

      UniProtKB/Swiss-Prot
      P15146

    11. XM_063266708.1 → XP_063122778.1  microtubule-associated protein 2 isoform X4

      UniProtKB/Swiss-Prot
      P15146

    12. XM_063266711.1 → XP_063122781.1  microtubule-associated protein 2 isoform X5

      UniProtKB/Swiss-Prot
      P15146

    13. XM_063266726.1 → XP_063122796.1  microtubule-associated protein 2 isoform X12

      UniProtKB/Swiss-Prot
      P15146

    14. XM_039083075.2 → XP_038939003.1  microtubule-associated protein 2 isoform X1

      UniProtKB/Swiss-Prot
      P15146
      UniProtKB/TrEMBL
      F1LNK0
      Conserved Domains (3) summary
      PTZ00449
      Location:1498 → 1772
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam08377
      Location:460 → 1593
      MAP2_projctn; MAP2/Tau projection domain
      pfam00418
      Location:1776 → 1806
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    15. XM_063266709.1 → XP_063122779.1  microtubule-associated protein 2 isoform X3

      UniProtKB/Swiss-Prot
      P15146

    16. XM_063266723.1 → XP_063122793.1  microtubule-associated protein 2 isoform X11

    17. XM_063266722.1 → XP_063122792.1  microtubule-associated protein 2 isoform X10

      UniProtKB/Swiss-Prot
      P15146

    18. XM_063266727.1 → XP_063122797.1  microtubule-associated protein 2 isoform X12

      UniProtKB/Swiss-Prot
      P15146

    19. XM_063266714.1 → XP_063122784.1  microtubule-associated protein 2 isoform X8

      UniProtKB/Swiss-Prot
      P15146
      UniProtKB/TrEMBL
      F1MAQ5

    20. XM_063266729.1 → XP_063122799.1  microtubule-associated protein 2 isoform X13

    21. XM_063266732.1 → XP_063122802.1  microtubule-associated protein 2 isoform X16

    22. XM_063266735.1 → XP_063122805.1  microtubule-associated protein 2 isoform X20

    23. XM_017596291.3 → XP_017451780.1  microtubule-associated protein 2 isoform X1

      UniProtKB/Swiss-Prot
      P15146
      UniProtKB/TrEMBL
      F1LNK0
      Related
      ENSRNOP00000050877.5, ENSRNOT00000045766.8
      Conserved Domains (3) summary
      PTZ00449
      Location:1498 → 1772
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam08377
      Location:460 → 1593
      MAP2_projctn; MAP2/Tau projection domain
      pfam00418
      Location:1776 → 1806
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    24. XM_017596297.3 → XP_017451786.1  microtubule-associated protein 2 isoform X6

      UniProtKB/TrEMBL
      A0A8I6GHK9
      Related
      ENSRNOP00000089734.1, ENSRNOT00000110600.2
      Conserved Domains (2) summary
      pfam00418
      Location:1776 → 1805
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:460 → 1593
      MAP2_projctn; MAP2/Tau projection domain

    25. XM_008767200.4 → XP_008765422.1  microtubule-associated protein 2 isoform X2

      UniProtKB/Swiss-Prot
      P15146
      Conserved Domains (2) summary
      pfam00418
      Location:1775 → 1804
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:460 → 1592
      MAP2_projctn; MAP2/Tau projection domain

    26. XM_039083078.2 → XP_038939006.1  microtubule-associated protein 2 isoform X7

      UniProtKB/TrEMBL
      A0A8I6GHK9
      Conserved Domains (3) summary
      PTZ00449
      Location:1498 → 1771
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam08377
      Location:460 → 1592
      MAP2_projctn; MAP2/Tau projection domain
      pfam00418
      Location:1806 → 1837
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    27. XM_008767199.4 → XP_008765421.1  microtubule-associated protein 2 isoform X3

      UniProtKB/Swiss-Prot
      P15146
      Conserved Domains (2) summary
      pfam00418
      Location:1775 → 1804
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:459 → 1592
      MAP2_projctn; MAP2/Tau projection domain

    28. XM_017596298.3 → XP_017451787.1  microtubule-associated protein 2 isoform X8

      UniProtKB/Swiss-Prot
      P15146
      UniProtKB/TrEMBL
      F1MAQ5
      Related
      ENSRNOP00000042029.6, ENSRNOT00000043627.9
      Conserved Domains (2) summary
      pfam00418
      Location:1694 → 1723
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:378 → 1511
      MAP2_projctn; MAP2/Tau projection domain

    29. XM_008767206.4 → XP_008765428.1  microtubule-associated protein 2 isoform X13

      UniProtKB/TrEMBL
      Q64715
      Conserved Domains (2) summary
      pfam00418
      Location:1694 → 1723
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:378 → 1511
      MAP2_projctn; MAP2/Tau projection domain

    30. XM_063266719.1 → XP_063122789.1  microtubule-associated protein 2 isoform X9

      UniProtKB/Swiss-Prot
      P15146
      Related
      ENSRNOP00000075849.3, ENSRNOT00000092445.3

    31. XM_039083083.2 → XP_038939011.1  microtubule-associated protein 2 isoform X14

      UniProtKB/TrEMBL
      Q64715
      Conserved Domains (3) summary
      PTZ00449
      Location:1416 → 1689
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam08377
      Location:378 → 1510
      MAP2_projctn; MAP2/Tau projection domain
      pfam00418
      Location:1724 → 1755
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    32. XM_008767205.4 → XP_008765427.1  microtubule-associated protein 2 isoform X11

      UniProtKB/Swiss-Prot
      P15146
      Conserved Domains (2) summary
      pfam00418
      Location:1690 → 1719
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:374 → 1507
      MAP2_projctn; MAP2/Tau projection domain

    33. XM_039083086.2 → XP_038939014.1  microtubule-associated protein 2 isoform X17

      UniProtKB/TrEMBL
      Q64715
      Conserved Domains (3) summary
      PTZ00449
      Location:1412 → 1685
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam08377
      Location:374 → 1506
      MAP2_projctn; MAP2/Tau projection domain
      pfam00418
      Location:1720 → 1751
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    34. XM_008767207.4 → XP_008765429.1  microtubule-associated protein 2 isoform X20

      See identical proteins and their annotated locations for XP_008765429.1

      UniProtKB/TrEMBL
      A0A0U1RS04, A0A9K3Y814, E9PTL3, Q78DZ1
      Related
      ENSRNOP00000031915.5, ENSRNOT00000037974.8
      Conserved Domains (1) summary
      pfam00418
      Location:332 → 361
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    35. XM_008767208.4 → XP_008765430.1  microtubule-associated protein 2 isoform X21

      See identical proteins and their annotated locations for XP_008765430.1

      UniProtKB/TrEMBL
      A0A0U1RS04, A6KFC7
      Conserved Domains (1) summary
      pfam00418
      Location:332 → 361
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    36. XM_039083077.2 → XP_038939005.1  microtubule-associated protein 2 isoform X5

      UniProtKB/Swiss-Prot
      P15146
      Conserved Domains (3) summary
      PTZ00449
      Location:1496 → 1770
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam08377
      Location:458 → 1591
      MAP2_projctn; MAP2/Tau projection domain
      pfam00418
      Location:1774 → 1804
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    37. XM_039083081.2 → XP_038939009.1  microtubule-associated protein 2 isoform X10

      UniProtKB/Swiss-Prot
      P15146
      Conserved Domains (3) summary
      PTZ00449
      Location:1415 → 1689
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam08377
      Location:377 → 1510
      MAP2_projctn; MAP2/Tau projection domain
      pfam00418
      Location:1693 → 1723
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    38. XM_039083084.2 → XP_038939012.1  microtubule-associated protein 2 isoform X15

      UniProtKB/TrEMBL
      Q64715
      Conserved Domains (3) summary
      PTZ00449
      Location:1415 → 1689
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam08377
      Location:377 → 1510
      MAP2_projctn; MAP2/Tau projection domain
      pfam00418
      Location:1724 → 1755
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    39. XM_039083082.2 → XP_038939010.1  microtubule-associated protein 2 isoform X12

      UniProtKB/Swiss-Prot
      P15146
      Conserved Domains (3) summary
      PTZ00449
      Location:1411 → 1685
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam08377
      Location:373 → 1506
      MAP2_projctn; MAP2/Tau projection domain
      pfam00418
      Location:1689 → 1719
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    40. XM_039083085.2 → XP_038939013.1  microtubule-associated protein 2 isoform X18

      UniProtKB/TrEMBL
      Q64715
      Conserved Domains (3) summary
      PTZ00449
      Location:1411 → 1685
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam08377
      Location:373 → 1506
      MAP2_projctn; MAP2/Tau projection domain
      pfam00418
      Location:1720 → 1751
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    41. XM_063266733.1 → XP_063122803.1  microtubule-associated protein 2 isoform X19

      UniProtKB/TrEMBL
      Q64715

    42. XM_063266737.1 → XP_063122807.1  microtubule-associated protein 2 isoform X22

      UniProtKB/TrEMBL
      A0A0U1RS04

    43. XM_063266710.1 → XP_063122780.1  microtubule-associated protein 2 isoform X3

      UniProtKB/Swiss-Prot
      P15146

    44. XM_063266716.1 → XP_063122786.1  microtubule-associated protein 2 isoform X8

      UniProtKB/Swiss-Prot
      P15146
      UniProtKB/TrEMBL
      F1MAQ5

    45. XM_063266730.1 → XP_063122800.1  microtubule-associated protein 2 isoform X13

      UniProtKB/TrEMBL
      Q64715

    46. XM_063266725.1 → XP_063122795.1  microtubule-associated protein 2 isoform X11

      UniProtKB/Swiss-Prot
      P15146

    47. XM_063266736.1 → XP_063122806.1  microtubule-associated protein 2 isoform X20

      UniProtKB/TrEMBL
      A0A0U1RS04, A0A9K3Y814, E9PTL3, Q78DZ1

    48. XM_063266712.1 → XP_063122782.1  microtubule-associated protein 2 isoform X5

      UniProtKB/Swiss-Prot
      P15146

    49. XM_063266721.1 → XP_063122791.1  microtubule-associated protein 2 isoform X10

      UniProtKB/Swiss-Prot
      P15146

    50. XM_063266728.1 → XP_063122798.1  microtubule-associated protein 2 isoform X12

      UniProtKB/Swiss-Prot
      P15146
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P15146.3 GenPept UniProtKB/Swiss-Prot:P15146

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