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    MIR193BHG MIR193b-365a host gene [ Homo sapiens (human) ]

    Gene ID: 100129781, updated on 10-Dec-2024

    Summary

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    Official Symbol
    MIR193BHGprovided by HGNC
    Official Full Name
    MIR193b-365a host geneprovided by HGNC
    Primary source
    HGNC:HGNC:51945
    See related
    Ensembl:ENSG00000262454 AllianceGenome:HGNC:51945
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HypERlnc; lincNORS
    Expression
    Broad expression in fat (RPKM 4.2), testis (RPKM 3.7) and 17 other tissues See more
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    Genomic context

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    See MIR193BHG in Genome Data Viewer
    Location:
    16p13.12
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (14301381..14331062)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (14338616..14368334)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (14395238..14424919)

    Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene myocardin related transcription factor B Neighboring gene uncharacterized LOC124903783 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr16:14339016-14340215 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:14375643-14376144 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr16:14377689-14378337 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:14379019-14380016 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10491 Neighboring gene Sharpr-MPRA regulatory region 5476 Neighboring gene tRNA-Thr (anticodon CGT) 2-1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7229 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:14396656-14396816 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7231 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:14400327-14401012 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:14401013-14401697 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10492 Neighboring gene Sharpr-MPRA regulatory regions 8431 and 11785 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10494 Neighboring gene microRNA 193b Neighboring gene microRNA 365a Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10495 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr16:14447139-14447668 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7232 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10496 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10497 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:14458211-14458712 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:14466520-14467096 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:14468174-14468349 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:14469696-14470196 Neighboring gene long intergenic non-protein coding RNA 2130 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:14487195-14487694 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:14499557-14500058 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10498 Neighboring gene Sharpr-MPRA regulatory region 5329 Neighboring gene Sharpr-MPRA regulatory region 2182 Neighboring gene long intergenic non-protein coding RNA 3107

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Expression of lncRNA MIR193BHG in serum of preeclampsia patients and its clinical significance. Dong N, et al. J Gynecol Obstet Hum Reprod, 2022 May. PMID 35301154
    2. Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS. Wu X, et al. Nat Commun, 2020 Sep 21. PMID 32958772, Free PMC Article
    3. Identification and Functional Characterization of Hypoxia-Induced Endoplasmic Reticulum Stress Regulating lncRNA (HypERlnc) in Pericytes. Bischoff FC, et al. Circ Res, 2017 Aug 4. PMID 28611075
    4. Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty. Cousminer DL, et al. Hum Mol Genet, 2014 Aug 15. PMID 24770850, Free PMC Article
    5. Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. Arking DE, et al. Nat Genet, 2014 Aug. PMID 24952745, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Expression of lncRNA MIR193BHG in serum of preeclampsia patients and its clinical significance.
      Title: Expression of lncRNA MIR193BHG in serum of preeclampsia patients and its clinical significance.
    2. Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS.
      Title: Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.
    EBI GWAS Catalog
    Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty.
    EBI GWAS Catalog
    Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Markers

    Other Names

    • MIR193B host
    • hypoxia-induced endoplasmic reticulum stress regulating long noncoding RNA
    • linc noncoding oxygen-sensitive regulator of sterol homeostasis
    • noncoding oxygen-sensitive regulator of sterol homeostasis

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_132983.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript.
      Source sequence(s)
      AC040173
      Related
      ENST00000641433.1

    2. NR_132984.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice site resulting in a shorter transcript, compared to variant 1.
      Source sequence(s)
      AC040173

    3. NR_170633.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate splice site resulting in a shorter transcript, compared to variant 1.
      Source sequence(s)
      AC040173

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

      Range
      14301381..14331062
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060940.1 Alternate T2T-CHM13v2.0

      Range
      14338616..14368334
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Research Materials